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Provedor de dados:  BJID
País:  Brazil
Título:  Clinical, endoscopic and prognostic aspects of primary gastric non-hodgkin's lymphoma associated with acquired immunodeficiency syndrome
Autores:  Rezende,Rosamar Eulira Fontes
Ferreira,Sandro da Costa
Hyppólito,Elodie Bomfim
Machado,Alcyone Artioli
Ardengh,José Celso
Módena,José Luiz Pimenta
Data:  2009-02-01
Ano:  2009
Palavras-chave:  Non-Hodgkin lymphoma
Upper digestive endoscopy
Resumo:  Primary gastric non-Hodgkin's lymphoma (NHL) is a co-morbidity that can be observed during the clinical course of acquired immunodeficiency syndrome (AIDS). We evaluated the prevalence, clinical-evolutive aspects and form of endoscopic presentation of primary gastric NHL associated with AIDS. Two hundred and forty-three HIV patients were submitted to upper digestive endoscopy, with evaluation of clinical, endoscopic and histological data. A CD4 count was made by flow cytometry and viral load was determined in a branched-DNA assay. Six cases (five men; mean age: 37 years; range: 29-46 years) of primary gastric NHL were detected. The median CD4 count was 140 cells/mm³ and the median viral load was 40,313 copies/mL. Upper digestive endoscopy revealed polypoid (in four patients) ulcero-infiltrative (two patients) and ulcerated (two patients) lesions and combined polypoid and ulcerated lesions (two patients). Histology of the gastric lesions demonstrated B cell NHL (four patients) and T cell NHL (two patients). Five of the six patients died of complications related to gastric NHL. We concluded that primary gastric NHL is an important cause of mortality associated with AIDS.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Editor:  Brazilian Society of Infectious Diseases
Relação:  10.1590/S1413-86702009000100002
Formato:  text/html
Fonte:  Brazilian Journal of Infectious Diseases v.13 n.1 2009
Direitos:  info:eu-repo/semantics/openAccess

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