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Provedor de dados:  BJM
País:  Brazil
Título:  Occurrence of killer Candida glabrata clinical isolates
Autores:  O,Arroyo-Helguera
Alejandro,De Las Penas
Irene,Castaño
Data:  2012-09-01
Ano:  2012
Palavras-chave:  Candida glabrata
Killer activity
Yeast
Saccharomyces
Resumo:  In this work we characterized the occurrence of killer activity in 64 Candida glabrata clinical isolates under different conditions. We found that only 6.25 % of the clinical isolates tested were positive for killer activity against a Saccharomyces cerevisiae W303 sensitive strain. Sensitivity of killer activity to different values of pH and temperatures was analyzed. We found that the killer activity presented by all isolates was resistant to every pH and temperature tested, although optimal activity was found at a range of pH values from 4 to 7 and at 37ºC. We did not observe extrachromosomal genetic elements associated with killer activity in any of the positive C. glabrata isolates. The killer effect was due to a decrease in viability and DNA fragmentation in sensitive yeast.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000300005
Editor:  Sociedade Brasileira de Microbiologia
Relação:  10.1590/S1517-83822012000300005
Formato:  text/html
Fonte:  Brazilian Journal of Microbiology v.43 n.3 2012
Direitos:  info:eu-repo/semantics/openAccess
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