| Registro completo |
| Provedor de dados: |
60
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| País: |
Brazil
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| Título: |
Development of a mouse computational model for MCNPx based on Digimouse (r) images and dosimetric assays
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| Autores: |
Mendes,Bruno Melo
Almeida,Iassudara Garcia de
Trindade,Bruno Machado
Fonseca,Telma Cristina Ferreira
Campos,Tarcísio Passos Ribeiro de
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| Data: |
2017-01-01
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| Ano: |
2017
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| Palavras-chave: |
Dosimetry/assay
Mouse phantom/tests
MCNPx Monte Carlo code Computational studies.
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| Resumo: |
ABSTRACT The aim of this study was to create and test a new mice 3D-voxel phantom named DM_BRA for mice and human first-estimation radiopharmaceutical dosimetry. Previously, the article reviews the state-of-art in animal model development. Images from Digimouse CT database were used in the segmentation and on the generation of the voxelized phantom. Simulations for validation of the DM_BRA model was performed at 0.015, 0.1, 0.5, 1 and 4 MeV photons with heart-source. Specific Absorbed Fractions (SAF) data were compared with literature data. The organ masses of DM_BRA correlated well with existing models based on the same dataset; however, few small organ masses hold significant variations. The SAF data in most simulated cases were statistically equal to a significant level of 0.01 to the reference data.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000100622
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| Editor: |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
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| Relação: |
10.1590/s2175-97902017000116092
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Pharmaceutical Sciences v.53 n.1 2017
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| Direitos: |
info:eu-repo/semantics/openAccess
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