| Registro completo |
| Provedor de dados: |
BJPS
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| País: |
Brazil
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| Título: |
Silver nanoparticles incorporated into nanostructured biopolymer membranes produced by electrospinning: a study of antimicrobial activity
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| Autores: |
Segala,Karen
Nista,Silvia Vaz Guerra
Cordi,Lívia
Bizarria,Maria Trindade Marques
Ávila Júnior,José de
Kleinubing,Sirlene Adriana
Cruz,Deborah Cristina
Brocchi,Marcelo
Lona,Liliane Maria Ferrareso
Caballero,Nelson Eduardo Durán
Mei,Lucia Helena Innocentini
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| Data: |
2015-12-01
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| Ano: |
2015
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| Palavras-chave: |
Electrospinning
Silver nanoparticles/antibacterial activity
Cellulose acetate
Chitosan
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| Resumo: |
abstract This study examines the antimicrobial activity of silver nanoparticles incorporated into nanostructured membranes made of cellulose acetate (CA) and blends of chitosan/poly-(ethylene oxide, CTS/PEO) and prepared by electrospinning. The formation of chemically synthesized Ag nanoparticles (AgNPs) was monitored by UV-visible spectroscopy (UV-Vis) and characterized by transmission electron microscopy (TEM). The size distribution of the AgNPs was measured by dynamic light scattering (DLS), with an average size of approximately 20 nm. The presence of AgNPs on the surface of electrospun nanofibers was observed by field emission electron microscopy (FEG) and confirmed by TEM. The antimicrobial activity of AgNPs incorporated into nanostructured membranes made of CA and CTS/PEO electrospun nanofibers was evaluated in the presence of both Gram-positive bacteria, such as Staphylococcus aureus ATCC 29213 and Propionibacterium acnes ATCC 6919, and Gram-negative bacteria, such as Escherichia coli ATCC 25992 and Pseudomonas aeruginosa ATCC 17933. Microbiological results showed that the presence of AgNPs in CA and CTS/PEO nanostructured membranes has significant antimicrobial activity for the Gram-positive bacteria Escherichia coli and Propionibacterium acnes.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000400911
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| Editor: |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
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| Relação: |
10.1590/S1984-82502015000400017
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Pharmaceutical Sciences v.51 n.4 2015
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| Direitos: |
info:eu-repo/semantics/openAccess
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