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Provedor de dados:  BJPS
País:  Brazil
Título:  Carbon nanotubes as a novel drug delivery system for anticancer therapy: a review
Autores:  Kushwaha,Swatantra Kumar Singh
Ghoshal,Saurav
Rai,Awani Kumar
Singh,Satyawan
Data:  2013-12-01
Ano:  2013
Palavras-chave:  Carbon nanotubes/properties
Carbon nanotubes/use
Carbon nanotubes/drugs delivery
Single-Walled Carbon Nanotube
Multiwalled Carbon Nanotube
Anticancer drugs/delivery
Cancer/therapy
Drugs/delivery
Resumo:  Carbon nanotubes (CNTs) were discovered in 1991 and shown to have certain unique physicochemical properties, attracting considerable interest in their application in various fields including drug delivery. The unique properties of CNTs such as ease of cellular uptake, high drug loading, thermal ablation, among others, render them useful for cancer therapy. Cancer is one of the most challenging diseases of modern times because its therapy involves distinguishing normal healthy cells from affected cells. Here, CNTs play a major role because phenomena such as EPR, allow CNTs to distinguish normal cells from affected ones, the Holy Grail in cancer therapy. Considerable work has been done on CNTs as drug delivery systems over the last two decades. However, concerns over certain issues such as biocompatibility and toxicity have been raised and warrant extensive research in this field.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400002
Editor:  Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
Relação:  10.1590/S1984-82502013000400002
Formato:  text/html
Fonte:  Brazilian Journal of Pharmaceutical Sciences v.49 n.4 2013
Direitos:  info:eu-repo/semantics/openAccess
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