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Provedor de dados:  Ciência Rural
País:  Brazil
Título:  Renal injury in female dogs with pyometra
Autores:  Figueiredo,Mariana da Silva
Malm,Christina
Mamão,Leonardo Dias
Oliveira,Juliana de
Veado,Júlio César Cambraia
Costa,Mariana Pádua
Valente,Pâmela Cristina Lopes Gurgel
Horta,Rodrigo dos Santos
Castro,Marina Lopes
Castro,Aline Gomes de
Sbaraini,Leila
Souza,Eliana Matias de
Data:  2017-01-01
Ano:  2017
Palavras-chave:  Kidney disease
Kidney function
Urinary GGT
Urinary protein-to-creatinine ratio
Glomerular filtration rate
Resumo:  ABSTRACT: Pyometra is a common disease in intact female dogs and can cause glomerulopathy and tubular injury. This study aimed to evaluate kidney injury in female dogs with pyometra, as well as progression of the injury during treatment and the markers of this condition. This study analyzed 20 intact female dogs with both clinical and sonographic diagnosis of pyometra. Dogs were treated with intravenous fluids and antibiotics, and an ovariohysterectomy was performed. The following parameters were assessed at eight separate time points: blood pressure; serum creatinine, phosphorus, and urea levels; urinalysis and urinary biochemical parameters [urinary gamma-glutamyl transferase (uGGT) and urinary protein-to-creatinine ratio (UPCR)]; glomerular filtration rate (GFR); and urine output. All dogs showed some degree of kidney injury at the time of pyometra diagnosis. This was transient in most animals, resolving with treatment of the pyometra. Measurement of uGGT and UPCR identified renal parenchymal injury, helping to determine the prognosis of the animals analyzed in the present study.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000500603
Editor:  Universidade Federal de Santa Maria
Relação:  10.1590/0103-8478cr20160325
Formato:  text/html
Fonte:  Ciência Rural v.47 n.5 2017
Direitos:  info:eu-repo/semantics/openAccess
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