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Provedor de dados:  Rev. Bras. Ciênc. Avic.
País:  Brazil
Título:  The Gene Ontology Differs in Bursa of Fabricius Between Two Breeds of Ducks Post Hatching by Enriching the Differentially Expressed Genes
Autores:  Liu,H
Data:  2018-03-01
Ano:  2018
Palavras-chave:  Bursa of Fabricius
Gene ontology
Digital gene expression profiling.
Resumo:  ABSTRACT The bursa of Fabricius (BF) is the central humoral immune organ unique to birds. The present study investigated the possible difference on a molecular level between two duck breeds. The digital gene expression profiling (DGE) technology was used to enrich the differentially expressed genes (DEGs) in BF between the Jianchang and Nonghua-P strains of ducks. DGE data identified 195 DEGs in the bursa. Gene Ontology (GO) analysis suggested that DEGs were mainly enriched in the metabolic pathways and ribosome components. Pathways analysis identified the spliceosome, RNA transport, RNA degradation process, Jak-STAT signaling pathway, TNF signaling pathway and B cell receptor signaling pathway. The results indicated that the main difference in the BF between the two duck strains was in the capabilities of protein formation and B cell development. These data have revealed the main divergence in the BF on a molecular level between genetically different duck breeds and may help to perform molecular breeding programs in poultry in the future.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Editor:  Fundação APINCO de Ciência e Tecnologia Avícolas
Relação:  10.1590/1806-9061-2016-0416
Formato:  text/html
Fonte:  Brazilian Journal of Poultry Science v.20 n.1 2018
Direitos:  info:eu-repo/semantics/openAccess

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