Consulta: creatorFacets:"戸瀬, 信一"
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Data/hora: 05/06/2024 18:15:48

20-Methylcholanthrene誘発腫瘍担癌マウスに対するトキソプラズマ溶解抗原の治療的投与効果
Provedor de dados: 19
Autores: 宮原, 和郎; 本多, 字里子; 戸瀬, 信一; 櫻井, 治久; 五十嵐, 郁男; 齋藤, 篤志; 広瀬, 恒夫; 鈴木, 直義; MIYAHARA, Kazuro.
Therapeutic effects of Toxoplasma lysate antigen (TLA) were studied in mice bearing the tumor in the second passage of 20-methylcholanthrene (MC)-induced tumor cells. Intramuscular administration of TLA 7 days after the tumor-cell inoculation caused apparent inhibition of the tumor growth on day 14. The second treatment facilitated the therapeutic effects. Intravenous transfer of spleen cells prepared from TLA-sensitized mice into tumor-bearing mice also represented the growth inhibitory effects. Prominent effects were seen when the transferred cells were prepared 5 days after sensitization of donor animals. The inhibitory effects were absent in the groups transferred only the adherent cells or the non-adherent cells prepared from sensitized mice. The...
Palavras-chave: Methylcholanthrene-induced tumor; Mouse spleen cell therapeutic effect Toxoplasma lysate antigen.
Ano: 1992
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4062