Consulta: creatorFacets:"BISPO,VANDERSON S."
Registros recuperados: 2
Data/hora: 04/06/2024 05:22:35

Reduction of the DNA damages, Hepatoprotective Effect and Antioxidant Potential of the Coconut Water, ascorbic and Caffeic Acids in Oxidative Stress Mediated by Ethanol
Provedor de dados: 42
Autores: BISPO,VANDERSON S.; DANTAS,LUCAS S.; CHAVES FILHO,ADRIANO B.; PINTO,ISABELLA F.D.; SILVA,RAILMARA P. DA; OTSUKA,FELIPE A.M.; SANTOS,RODRIGO B.; SANTOS,ALINE C.; TRINDADE,DANIELLE J.; MATOS,HUMBERTO R.
ABSTRACT Hepatic disorders such as steatosis and alcoholic steatohepatitis are common diseases that affect thousands of people around the globe. This study aims to identify the main phenol compounds using a new HPLC-ESI+-MS/MS method, to evaluate some oxidative stress parameters and the hepatoprotective action of green dwarf coconut water, caffeic and ascorbic acids on the liver and serum of rats treated with ethanol. The results showed five polyphenols in the lyophilized coconut water spiked with standards: chlorogenic acid (0.18 µM), caffeic acid (1.1 µM), methyl caffeate (0.03 µM), quercetin (0.08 µM) and ferulic acid (0.02 µM) isomers. In the animals, the activity of the serum γ-glutamyltranspeptidase (γ-GT) was reduced to 1.8 I.U/L in the coconut...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Coconut water; Ethanol; Oxidative stress; Phenolic compounds.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000301095

Evaluation of Chemical Constituents and Antioxidant Activity of Coconut Water (Cocus nucifera L.) and Caffeic Acid in Cell Culture
Provedor de dados: 42
Autores: SANTOS,JOãO L.A.; BISPO,VANDERSON S.; B.C. FILHO,ADRIANO; PINTO,ISABELLA F.D.; DANTAS,LUCAS S.; VASCONCELOS,DAIANE F.; ABREU,FABíULA F.; MELO,DANILO A.; MATOS,ISAAC A.; FREITAS,FLORêNCIO P.; GOMES,OSMAR F.; MEDEIROS,MARISA H.G.; MATOS,HUMBERTO R.
Coconut water contains several uncharacterized substances and is widely used in the human consumption. In this paper we detected and quantified ascorbic acid and caffeic acid and total phenolics in several varieties of coconut using HPLS-MS-MS (25.8 ± 0.6 µg-mL and 1.078 ± 0.013 µg-mL and 99.7 µg-mL, respectively, in the green dwarf coconut water, or 10 mg and 539 µg and 39.8 mg for units of coconut consumed, 500 ± 50 mL). The antioxidant potential of four coconut varieties (green dwarf, yellow dwarf, red dwarf and yellow Malaysian) was compared with two industrialized coconut waters and the lyophilized water of the green dwarf variety. All varieties were effective in scavenging the DPPH radical (IC50=73 µL) and oxide nitric (0.1 mL with an IP of 29.9%) as...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antioxidant activity; Ascorbic acid; Caffeic acid; Cocos nucifera; Polyphenols.
Ano: 2013
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000401235