Consulta: creatorFacets:"Bawaskar,H. S."
Registros recuperados: 2
Data/hora: 01/06/2024 16:49:27

Management of severe scorpion sting at rural settings: what is the role of scorpion antivenom?
Provedor de dados: Journal of Venomous Animals and Toxins Including Tropical Diseases
Autores: Bawaskar,H. S.
Tipo: Info:eu-repo/semantics/other
Ano: 2005
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992005000100002

Novel role of antiplatelet agents (aspirin plus clopidogrel) in an incoagulable blood of a victim of russell's viper snakebite
Provedor de dados: Journal of Venomous Animals and Toxins Including Tropical Diseases
Autores: Bawaskar,H. S.
Snake antivenom is a specific antidote to the venom action, neutralizing the circulating venom. However, it fails to neutralize the venom fixed to target organs such as platelets, renal tubules, etc. Russell's viper venom initiates rapid coagulation in a victim by activating blood platelets, factors V, X, and anticoagulant cofactors. Activation of thrombin, resulting in formation of micro-thrombi, fibrinolysis, and a vicious cascade, sets in. Inhibition of activated platelets by aspirin (cyclooxygenase inhibitor) and clopidogrel (ADP receptor inhibitor) helps to break this vicious circle induced by Russell's venom and may initiate the natural physiological clotting mechanism. They can be utilized as an adjuvant treatment.
Tipo: Info:eu-repo/semantics/report
Palavras-chave: Russell's viper; Coagulation; Fibrinolysis; Aspirin; Clopidogrel.
Ano: 2006
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000100011