Consulta: creatorFacets:"Bocianowski,Jan"
Registros recuperados: 3
Data/hora: 05/06/2024 03:40:41

Epistasis interaction of QTL effects as a genetic parameter influencing estimation of the genetic additive effect
Provedor de dados: 74
Autores: Bocianowski,Jan.
Epistasis, an additive-by-additive interaction between quantitative trait loci, has been defined as a deviation from the sum of independent effects of individual genes. Epistasis between QTLs assayed in populations segregating for an entire genome has been found at a frequency close to that expected by chance alone. Recently, epistatic effects have been considered by many researchers as important for complex traits. In order to understand the genetic control of complex traits, it is necessary to clarify additive-by-additive interactions among genes. Herein we compare estimates of a parameter connected with the additive gene action calculated on the basis of two models: a model excluding epistasis and a model with additive-by-additive interaction effects....
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Additive gene action effect; Barley; Doubled haploid lines; Epistasis; QTL.
Ano: 2013
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000100013

The use of weighted multiple linear regression to estimate QTL-by-QTL epistatic effects
Provedor de dados: 74
Autores: Bocianowski,Jan.
Knowledge of the nature and magnitude of gene effects, as well as their contribution to the control of metric traits, is important in formulating efficient breeding programs for the improvement of plant genetics. Information concerning a genetic parameter such as the additive-by-additive epistatic effect can be useful in traditional breeding. This report describes the results obtained by applying weighted multiple linear regression to estimate the parameter connected with an additive-by-additive epistatic interaction. Three weight variants were used: (1) standard weights based on estimated variances, (2) different weights for minimal, maximal and other lines, and (3) different weights for extreme and other lines. The approach described here combines two...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Biometrical genetics; Epistatic interaction; Homozygous lines; QTL; Simulation study; Weighted regression.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000500015

Analytical and numerical comparisons of two methods of estimation of additive × additive interaction of QTL effects
Provedor de dados: 63
Autores: Bocianowski,Jan.
Epistasis (additive × additive interaction) plays an important role in the genetic architecture of complex traits. This study presents analytical and numerical comparisons of two methods of estimation of additive × additive interaction of QTL effects. In the first method, we observed only the plant phenotype, while in the second method we have additional information from the molecular markers observations. In this study, two data sets were analyzed: i) 150 barley (Hordeum vulgare L.) doubled-haploid lines derived from the cross Steptoe × Morex and ii) 145 doubled-haploid lines of barley obtained from the cross Harrington × TR306. In total, 153 sets of observations were analyzed. The additive × additive interaction effect calculated on the basis of the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Nonallelic interaction effect; Doubled haploid lines; Quantitative trait loci.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162012000400002