Consulta: creatorFacets:"Bouzas,Luiz Fernando"
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Data/hora: 10/06/2024 08:14:19

Monosomy 7 in donor cell-derived leukemia after bone marrow transplantation for severe aplastic anemia: report of a new case and review of the literature
Provedor de dados: 74
Autores: Otero,Luize; Souza,Daiane Correa de; Tavares,Rita de Cássia; Gomes,Bernadete Evangelho; Padilha,Telma França; Bouzas,Luiz Fernando; Fernandez,Teresa de Souza; Abdelhay,Eliana.
Monosomy 7 arises as a recurrent chromosome aberration in donor cell leukemia after hematopoietic stem cell transplantation. We report a new case of donor cell leukemia with monosomy 7 following HLA-identical allogenic bone marrow transplantation for severe aplastic anemia (SAA). The male patient received a bone marrow graft from his sister, and monosomy 7 was detected only in the XX donor cells, 34 months after transplantation. The patient's bone marrow microenvironment may have played a role in the leukemic transformation of the donor hematopoietic cells.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Monosomy 7; Donor cell leukemia; Bone marrow transplantation; Severe aplastic anemia.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000500004