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Antineoplastic potential of the aqueous crude extract of Eugenia uniflora L. in human cervical cancer
Provedor de dados: Brazilian Journal of Pharmaceutical Sciences
Autores: Núñez,Jisette González; Pinheiro,Jordânia dos Santos; Silveira,Gabriel Fernandes; Beckenkamp,Aline; Buffon,Andréia; Bruno,Alessandra Nejar.
Abstract Considering the high prevalence of human cervical cancer and the adverse effects of the available treatments, it is important to develop studies involving plants. Eugenia uniflora L. is a Brazilian native plant widely used in folk medicine and some biological effects have already been described. In this study, we investigated the biologicals effects of the aqueous crude extract of E. uniflora leaves in relation to the viability of human cervical cancer cells (SiHa), non-tumorigenic cells HaCaT and human lymphocytes. Our results demonstrated that different concentrations of E. uniflora’s extract significantly inhibited the viability of the Siha cell line at 24, 48 and 72 hours of treatment, but did not induce significant changes in the HaCat cell...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Eugenia uniflora L./effects/antitumoral; Pitangueira; SiHa; HaCat; Plant extract/antitumoral; Cervical cancer.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000200618