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Data/hora: 16/06/2024 09:34:15

Antioxidant Capacity and Acute Testicular Toxicity of Leucaena leucocephala Aqueous Shoot Tips Plus Young Leaves Extracts
Provedor de dados: 77
Autores: Burawat,Jaturon; Uabandit,Nongnut; Sripanidkulchai,Bungorn; Nualkaew,Somsak; Iamsaard,Sitthichai.
This study aimed to determine the antioxidant capacity of the Leucaena leucocephala aqueous shoot tips plus young leaves (LL-spl) extracts among three different fractions (LL-spl 10, 20, and 40 min) and to examine its acute toxicity on male reproductive parameters. The amount of the total phenolics in LL-spl extract was determined using a Folin-Ciocalteu reagent method and its antioxidant capacity was analyzed using 1, 1-diphenyl l-2-picrylhydrazyl radical scavenging and ferric reducing antioxidant powder methods. The LL-spl extract fraction with highest antioxidant capacity was used in animal treating. Male rats were divided into three groups (n= 5); control and groups treated with LL-spl 400 and 600 mg/Kg body weight for consecutive 40 days. The results...
Tipo: Journal article
Palavras-chave: Leucaena leucocephala; Shoot tips plus young leaves; Antioxidant capacity; Acute testicular toxicity.
Ano: 2016
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000200018

Phyllanthus emblica L. Branch Extract Ameliorates Testicular Damage in Valproic Acid-Induced Rats
Provedor de dados: 77
Autores: Iamsaard,Sitthichai; Arun,Supatcharee; Burawat,Jaturon; Sukhorum,Wannisa; Boonruangsri,Porntip; Namking,Malivalaya; Uabundit,Nongnut; Nualkaew,Somsak; Sripanidkulchai,Bungorn.
Valproic acid (VPA), widely used in treating epileptic patients, can damage reproductive parameters causing male infertility. This study aimed to investigate protective effect of Phyllanthus emblica L. branch (PE) extract on rat testicular damage induced with VPA. Male rats were divided into 6 groups (control, VPA, 250 mg/kgBW PE only, and 50, 100, 250 mg/kgBW PE+VPA, respectively). Animals were pretreated with PE for 23 days and co-administered with VPA for 10 days before all reproductive parameters were determined. The results showed all doses of PE significantly protected the decrease testicular weight and testosterone level in VPA rats. PE significantly improved the decrease sperm concentration in VPA treated rats. Moreover, testicular histology of...
Tipo: Journal article
Palavras-chave: Valproic acid; Phyllanthus emblica L; Testicular damage; Rats.
Ano: 2015
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000300033

Antioxidant and Hypoglycemic Effects of Momordica cochinchinensis Spreng: (Gac) Aril Extract on Reproductive Damages in Streptozotocin (STZ)-Induced Hyperglycemia Mice
Provedor de dados: 77
Autores: Sampannang,Apichakan; Arun,Supatcharee; Sukhorum,Wannisa; Burawat,Jaturon; Nualkaew,Somsak; Maneenin,Chanwit; Sripanidkulchai,Bungorn; Iamsaard,Sitthichai.
The aim of present study was to investigate the effect of Momordica cochinchinensis (Gag) aril (GA) aqueous extract on male reproductive system of streptozotocin (STZ)-induced hyperglycemia (HG) mice. GA were extracted with distilled water (DW) and analyzed for in vitro antioxidant capacities. ICR male mice were divided into 7 groups: 1) control, 2) DW, 3) GA 1000 mg/kg BW, 4) HG, 5) HG + glibenclamide, 6 and 7) HG + GA 500 and 1000 mg/kg BW respectively (7 mice/ group). In HG groups, mice were induced by STZ at single dose (150 mg/kg BW). They were treated for consecutive 35 days. All groups were compared for blood glucose levels, weights and histopathologies of reproductive organs, sperm concentration including testicular tyrosine phosphorylation protein...
Tipo: Journal article
Palavras-chave: Momordica cochinchinensis aril; Streptozotocin (STZ); Testicular damage; Testicular tyrosine phosphorylated protein; Hyperglycemia (HG) mice.
Ano: 2017
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000200046