Consulta: creatorFacets:"Chan, Philippe"
Registros recuperados: 2
Data/hora: 16/06/2024 16:57:58

Deciphering the molecular mechanisms of mother-to-egg immune protection in the mealworm beetle Tenebrio molitor
Provedor de dados: 5
Autores: Tetreau, Guillaume; Dhinaut, Julien; Galinier, Richard; Audant-lacour, Pascaline; Voisin, Sébastien N; Arafah, Karim; Chogne, Manon; Hilliou, Frédérique; Bordes, Anaïs; Sabarly, Camille; Chan, Philippe; Walet-balieu, Marie-laure; Vaudry, David; Duval, David; Bulet, Philippe; Coustau, Christine; Moret, Yannick; Gourbal, Benjamin.
In a number of species, individuals exposed to pathogens can mount an immune response and transmit this immunological experience to their offspring, thereby protecting them against persistent threats. Such vertical transfer of immunity, named trans-generational immune priming (TGIP), has been described in both vertebrates and invertebrates. Although increasingly studied during the last decade, the mechanisms underlying TGIP in invertebrates are still elusive, especially those protecting the earliest offspring life stage, i.e. the embryo developing in the egg. In the present study, we combined different proteomic and transcriptomic approaches to determine whether mothers transfer a “signal” (such as fragments of infecting bacteria), mRNA and/or...
Tipo: Text
Ano: 2020
URL: https://archimer.ifremer.fr/doc/00655/76684/77815.pdf

Double impact: natural molluscicide for schistosomiasis vector control also impedes development of Schistosoma mansoni cercariae into adult parasites
Provedor de dados: 5
Autores: Augusto, Ronaldo De Carvalho; Tetreau, Guillaume; Chan, Philippe; Walet-balieu, Marie-laure; Mello-silva, Clelia Christina; Santos, Claudia Portes; Grunau, Christoph.
Background Schistosomiasis has been reported in 78 endemic countries and affects 240 million people worldwide. The digenetic parasite Schistosoma mansoni needs fresh water to compete its life cycle. There, it is susceptible to soluble compounds that can affect directly and/or indirectly the parasite's biology. The cercariae stage is one of the key points in which the parasite is vulnerable to different soluble compounds that can significantly alter the parasite's life cycle. Molluscicides are recommended by the World Health Organization for the control of schistosomiasis transmission and Euphorbia milii latex is effective against snails intermediate hosts. Methodology/Principal findings We used parasitological tools and electron microscopy to verify the...
Tipo: Text
Ano: 2017
URL: https://archimer.ifremer.fr/doc/00398/50960/71803.tif