Consulta: creatorFacets:"Chattipakorn,S."
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Data/hora: 29/05/2024 05:56:15

Effect of sildenafil citrate on the cardiovascular system
Provedor de dados: 56
Autores: Shinlapawittayatorn,K.; Chattipakorn,S.; Chattipakorn,N.
Sildenafil citrate is a drug commonly used to manage erectile dysfunction. It is designated chemically as 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H -pyrazolo[4,3-d]pyrimidin-5-yl)-4 ethoxyphenyl] sulfonyl]-4-methylpiperazine citrate (C22H30N6O4 S). It is a highly selective inhibitor of cyclic guanine monophosphate-specific phosphodiesterase type 5. In late March through mid-November 1998, the US Food and Drug Administration (FDA) published a report on 130 confirmed deaths among men (mean age, 64 years) who received prescriptions for sildenafil citrate, a period during which &gt;6 million outpatient prescriptions (representing about 50 million tablets) were dispensed. The US FDA recently reported that significant cardiovascular events, including sudden...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Sildenafil citrate; Erectile dysfunction; Sudden cardiac death; Cardiovascular disease; Phosphodiesterase inhibitor; Cardioprotection.
Ano: 2005
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000900003