Consulta: creatorFacets:"Chen,X.Y."
Registros recuperados: 3
Data/hora: 09/06/2024 18:22:32

Investigating ego modules and pathways in osteosarcoma by integrating the EgoNet algorithm and pathway analysis
Provedor de dados: 56
Autores: Chen,X.Y.; Chen,Y.H.; Zhang,L.J.; Wang,Y.; Tong,Z.C.
Osteosarcoma (OS) is the most common primary bone malignancy, but current therapies are far from effective for all patients. A better understanding of the pathological mechanism of OS may help to achieve new treatments for this tumor. Hence, the objective of this study was to investigate ego modules and pathways in OS utilizing EgoNet algorithm and pathway-related analysis, and reveal pathological mechanisms underlying OS. The EgoNet algorithm comprises four steps: constructing background protein-protein interaction (PPI) network (PPIN) based on gene expression data and PPI data; extracting differential expression network (DEN) from the background PPIN; identifying ego genes according to topological features of genes in reweighted DEN; and collecting ego...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Osteosarcoma; Ego; Genes; Modules; Pathways.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000200607

Detection of human cytomegalovirus DNA in various blood components after liver transplantation
Provedor de dados: 56
Autores: Chen,X.Y.; Hou,P.F.; Bi,J.; Ying,C.M.
The quantification of human cytomegalovirus (HCMV DNA) by real-time PCR is currently a primary option for laboratory diagnosis of HCMV infection. However, the optimal sample material remains controversial due to the use of different PCR assays. To explore the best blood component for HCMV DNA surveillance after liver transplantation, whole blood (WB), serum (SE), and plasma (PL) specimens were collected simultaneously from targeted patients and examined for HCMV DNA using one commercially available assay. The HCMV DNA-positive rate with WB (16.67%) was higher than that with either SE or PL (8.33%, both P&lt;0.01). Quantitative DNA levels in WB were of greater magnitude than those in SE (WB-SE mean log-transformed difference, 0.99; 95%CI=0.74-1.25;...
Palavras-chave: HCMV DNA; Blood components; Real-time quantitative PCR; Liver transplantation.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000400340

Duodenal gastric metaplasia and Helicobacter pylori infection in patients with diffuse nodular duodenitis
Provedor de dados: 56
Autores: Li,X.B.; Ge,Z.Z.; Chen,X.Y.; Liu,W.Z.
Whether the regression of gastric metaplasia in the duodenum can be achieved after eradication of Helicobacter pylori is not clear. The aim of the present study was to investigate the relationship between H. pylori infection and gastric metaplasia in patients with endoscopic diffuse nodular duodenitis. Eighty-six patients with endoscopically confirmed nodular duodenitis and 40 control patients with normal duodenal appearance were investigated. The H. pylori-positive patients with duodenitis received anti-H. pylori triple therapy (20 mg omeprazole plus 250 mg clarithromycin and 400 mg metronidazole, all twice daily) for one week. A control endoscopy was performed 6 months after H. pylori treatment. The H. pylori-negative patients with duodenitis received 20...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Nodular duodenitis; Helicobacter pylori; Gastric metaplasia.
Ano: 2007
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000700002