Consulta: creatorFacets:"Costa,Deise A."
Registros recuperados: 1
Data/hora: 10/06/2024 07:55:27

Balanced cytokine-producing pattern in mice immunized with an avirulent Trypanosoma cruzi
Provedor de dados: Anais da Academia Brasileira de Ciências
Autores: Soares,Milena B. P.; Gonçalves,Renata; Pyrrho,Alexandre S.; Costa,Deise A.; Paiva,Claudia N.; Gattass,Cerli R.
We have previously demonstrated that inoculation of BALB/c mice with trypomastigotes of CL-14, an avirulent Trypanosoma cruzi clone, prevents the development of parasitemia and mortality after challenge with virulent CL strain. In this report, we investigated the cytokine and antibody profiles induced by inoculation with CL-14 clone. Groups of mice were inoculated with trypomastigotes of CL-14 clone and challenged with infective CL strain. Challenged CL-14-inoculated mice had lower levels of IFN-&lt;FONT FACE=Symbol&gt;g&lt;/font&gt; and higher production of IgG1 antibodies as compared to CL strain-infected mice. Previous inoculation with CL-14 clone partially prevented the suppression of IL-2 production caused by CL strain infection. No significant...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Trypanosoma cruzi; Protection; Cytokines; Humoral response.
Ano: 2003
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652003000200005