Consulta: creatorFacets:"Derakhshandeh,Abdollah"
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Assessment of immunity against avian colibacillosis induced by an aroA mutant containing increased serum survival gene in broilers
Provedor de dados: 58
Autores: Salehi,Taghi Zahraei; Tabatabaei,Saeid; Karimi,Vahid; Fasaei,Bahar Nayeri; Derakhshandeh,Abdollah; Jahromi,Omid Ali Nekoui.
Colibacillosis is an important disease in the poultry industry which causes serious economic damages. As it is suggested that vaccination is one of the means to control colibacillosis, we tried to investigate the vaccine potential of a ΔaroA derivative of an O78:K80 avian pathogenic Escherichia coli containing increased serum survival gene. 490 chicks were selected as follows: For assessment of virulence of ΔaroA mutant, 30 chicks were divided into three groups and injected with 0.5ml of PBS or bacterial suspension containing either10(7)colony forming units (CFU) of mutant or parent strains via subcutaneous route. Macroscopic lesions and mortality rate were recorded in different groups during the week after challenge. For assessment of safety and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Chickens; Avian pathogenic Escherichia coli; ΔaroA mutant; Vaccine.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000100043