Consulta: creatorFacets:"Disconzi, Elena"
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Data/hora: 08/06/2024 18:42:03

csrB Gene Duplication Drives the Evolution of Redundant Regulatory Pathways Controlling Expression of the Major Toxic Secreted Metalloproteases in Vibrio tasmaniensis LGP32
Provedor de dados: 5
Autores: Nguyen, An Ngoc; Disconzi, Elena; Charriere, Guillaume; Destoumieux-garzon, Delphine; Bouloc, Philippe; Le Roux, Frederique; Jacq, Annick.
CsrBs are bacterial highly conserved and multiple-copy noncoding small RNAs (sRNAs) that play major roles in cell physiology and virulence. In the Vibrio genus, they are known to be regulated by the two-component system VarSNarA. They modulate the well-characterized quorum sensing pathway controlling virulence and luminescence in Vibrio cholerae and Vibrio harveyi, respectively. Remarkably, Vibrio tasmaniensis LGP32, an oyster pathogen that belongs to the Splendidus Glade, was found to have four copies of csrB, named csrB1-4, compared to two to three copies in other Vibrio species. Here, we show that the extra csrB4 copy results from a csrB3 gene duplication, a characteristic of the Splendidus Glade. Interestingly, csrB genes are regulated in different...
Tipo: Text
Palavras-chave: Bacterial gene regulation; Bacterial sRNAs; Transcriptomics; Vibrio pathogenic to oysters; Host-pathogen interactions.
Ano: 2018
URL: https://archimer.ifremer.fr/doc/00476/58785/61319.pdf