Consulta: creatorFacets:"El Beitune,Patrícia"
Registros recuperados: 3
Data/hora: 10/06/2024 13:37:02

Effects of antiretroviral agents during pregnancy on liver enzymes and amylase in HIV-exposed, uninfected newborn infants
Provedor de dados: Brazilian Journal of Infectious Diseases
Autores: El Beitune,Patrícia; Duarte,Geraldo; Campbell,Oona; Quintana,Silvana Maria; Rodrigues,Laura C.
This study assessed the effect of antiretroviral drugs administered to pregnant women on amylase and liver enzymes of the neonate. A prospective study was conducted on 52 neonates divided into three groups: infants born to HIV-infected mothers taking zidovudine (ZDV group, n = 18), infants born to mothers taking zidovudine + lamivudine + nelfinavir (TT group, n = 22) and infants born to normal women (control group, n = 12). Umbilical cord blood from the newborn infant was used to determine liver transaminases and amylase. Data were analyzed statistically by nonparametric tests, with the level of significance set at p&lt;0.05. The median levels for TT group newborns were 33.3 U/L for oxaloacetic transaminase, 21.5 U/L for pyruvic transaminase, 1.9 mg/dL for...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Combination antiretroviral therapy; Hypothesis generation; Infant toxicity; Umbilical cord blood.
Ano: 2007
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000300003

Colonization by Streptococcus agalactiae during pregnancy: maternal and perinatal prognosis
Provedor de dados: Brazilian Journal of Infectious Diseases
Autores: El Beitune,Patrícia; Duarte,Geraldo; Maffei,Cláudia Maria Leite.
We reviewed colonization by group B Streptococcus beta-haemolyticus of Lancefield (SGB), or Streptococcus agalactiae, in pregnant women, and the consequences of infection for the mother and newborn infant, including factors that influence the risk for anogenital colonization by SGB. We also examined the methods for diagnosis and prophylaxis of SGB to prevent early-onset invasive neonatal bacterial disease. At present, it is justifiable to adopt anal and vaginal SGB culture as part of differentiated obstetrical care in order to reduce early neonatal infection. The rates, risk factors of maternal and neonatal SGB colonization, as well as the incidence of neonatal disease, may vary in different communities and need to be thoroughly evaluated in each country...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Pregnancy; Prognosis; Streptococcus agalactiae.
Ano: 2005
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000400002

Antiretroviral therapy during pregnancy and early neonatal life: consequences for HIV-exposed, uninfected children
Provedor de dados: Brazilian Journal of Infectious Diseases
Autores: El Beitune,Patrícia; Duarte,Geraldo; Quintana,Silvana Maria; Figueiró-Filho,Ernesto A.; Marcolin,Alessandra Cristina; Abduch,Renata.
Women have emerged as the fastest growing human immunodeficiency virus (HIV) infected population worldwide, mainly because of the increasing occurrence of heterosexual transmission. Most infected women are of reproductive age and one of the greatest concerns for both women and their physicians is that more than 1,600 infants become infected with HIV each day. Almost all infections are a result of mother-to-child transmission of HIV. With the advent of combination antiretroviral therapies, transmission rates lower than 2% have been achieved in clinical studies. Antiretroviral compounds differ from most other new pharmaceutical agents in that they have become widely prescribed in pregnancy in the absence of proof of safety. We reviewed antiretroviral agents...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: HIV-1; Exposed; Infant; Consequences; Antiretroviral.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000200004