Consulta: creatorFacets:"Gentil,V."
Registros recuperados: 2
Data/hora: 29/05/2024 05:31:16

Dose-related effects of propericiazine in rats
Provedor de dados: 56
Autores: Cechin,E.M.; Quevedo,J.; Barichello,T.; Machado-Vieira,R.; Gentil,V.; Kapczinski,F.
We evaluated the effects of the neuroleptic agent propericiazine on animal models of anxiety and memory. Adult male Wistar rats (250 to 350 g) received intraperitoneal injections of propericiazine (0.05, 0.075 and 0.1 mg/kg), diazepam (1 mg/kg), saline, or diazepam vehicle (20% propylene glycol and 80% saline) 30 min prior to the experimental procedure. Animals (10-15 for each task) were tested for step-down inhibitory avoidance (0.3-mA footshock) and habituation to an open-field for memory assessment, and submitted to the elevated plus-maze to evaluate the effects of propericiazine in a model of anxiety. Animals treated with 0.075 mg/kg propericiazine showed a reduction in anxiety measures (P&lt;0.05) similar to that observed in those treated with...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Propericiazine; Memory; Anxiety; Diazepam; Elevated plus-maze.
Ano: 2003
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000200010

Engagement of multifocal neural circuits during recall of autobiographical happy events
Provedor de dados: 56
Autores: Cerqueira,C.T.; Almeida,J.R.C.; Gorenstein,C.; Gentil,V.; Leite,C.C.; Sato,J.R.; Amaro Jr.,E.; Busatto,G.F.
Happy emotional states have not been extensively explored in functional magnetic resonance imaging studies using autobiographic recall paradigms. We investigated the brain circuitry engaged during induction of happiness by standardized script-driven autobiographical recall in 11 healthy subjects (6 males), aged 32.4 ± 7.2 years, without physical or psychiatric disorders, selected according to their ability to vividly recall personal experiences. Blood oxygen level-dependent (BOLD) changes were recorded during auditory presentation of personal scripts of happiness, neutral content and negative emotional content (irritability). The same uniform structure was used for the cueing narratives of both emotionally salient and neutral conditions, in order to...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Functional magnetic resonance imaging; Autobiographical recall; Emotion induction; Affective states.
Ano: 2008
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001200006