Consulta: creatorFacets:"Gimenes Teixeira,H.L."
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Data/hora: 10/06/2024 07:58:46

The role of micro-ribonucleic acids in normal hematopoiesis and leukemic T-lymphogenesis
Provedor de dados: 56
Autores: Slavov,S.N.; Gimenes Teixeira,H.L.; Rego,E.M.
Micro-ribonucleic acids (microRNAs) are small molecules containing 20-23 nucleotides. Despite their small size, it is likely that almost every cellular process is regulated by them. Moreover, aberrant microRNA expression has been involved in the development of various diseases, including cancer. Although many data are available about the role of microRNAs in various lymphoproliferative disorders, their impact on the development of acute lymphoblastic leukemia of T-cell progenitors is largely unknown. In this review, we present recent information about how specific microRNAs are expressed and regulated during malignant T-lymphopoiesis and about their role during normal hematopoiesis.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: MicroRNAs; Gene expression; Leukemia; Acute lymphoblastic leukemia; T cells.
Ano: 2010
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000700003