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Epstein-Barr virus DNA load and its association with Helicobacter pylori infection in gastroduodenal diseases
Provedor de dados: 55
Autores: Shukla,Sanket Kumar; Prasad,K.N; Tripathi,Aparna; Singh,Avinash; Saxena,Ashish; Ghoshal,Uday Chand; Krishnani,Narendra; Husain,Nuzhat.
Helicobacter pylori and Epstein-Barr virus (EBV) infections are common worldwide. Although H. pylori infection is a major factor in gastroduodenal diseases, its role in association with EBV infection is unknown. Objective: To study the association of H. pylori infection and EBV DNA load in patients with gastroduodenal diseases. Methods: Biopsy samples were collected from 200 adult patients [non-ulcer dyspepsia (NUD) 100, peptic ulcer disease (PUD) 50, gastric carcinoma (GC) 50] undergoing upper gastrointestinal endoscopy. H. pylori infection was diagnosed by rapid urease test, culture, histopathology, PCR and Q-PCR. EBV DNA was detected by non-polymorphic Epstein-Barr nuclear antigen-1 (EBNA-1) gene based Q-PCR. Results: In patients with GC and PUD, EBV...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Epstein-Barr virus infections; Stomach neoplasms; Helicobacter pylori.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000600014