Consulta: creatorFacets:"Hyslop,S."
Registros recuperados: 2
Data/hora: 16/06/2024 10:16:57

Rabbit antivenom efficacy against myotoxic and neurotoxic activities of Bothrops jararacussu venom and bothropstoxin-I
Provedor de dados: 79
Autores: Oshima-Franco,Y.; Leite,G. B.; Valério,A. A.; Hyslop,S.; Andriao-Escarso,S.; Giglio,J. R.; Prado-Franceschi,J.; Cruz-Höfling,M. A.; Rodrigues-Simioni,L.
Bothrops jararacussu venom and its major toxin bothropstoxin-I (BthTX-I) possess myotoxic and neurotoxic properties. The efficacy of a rabbit antivenom raised against B. jararacussu venom in the neutralization of physiological, biochemical, and morphological changes induced by the venom and its major toxin BthTX-I was studied in mouse isolated phrenic nerve-diaphragm (PND) and extensor digitorum longus (EDL) preparations. The times required for 50% neuromuscular blockade in PND and EDL preparations for venom were 70+11.5 (S.E.M., n=5) min and 58+8 (n=16) (50 mu g/mL), and for BthTX-I 31+6 (n=3) min and 30+3 (n=5) min (20 mu g/mL), respectively. After 120 min incubation, creatine kinase (CK) concentrations in solution containing the EDL preparations were...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Bothrops venom; Myotoxin; Neutralization; Neuromuscular junction; Histological analysis; Bothrops jararacussu.
Ano: 2002
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302002000200004

COMPLETE AMINO ACID SEQUENCE OF AN ASP49 PHOSPHOLIPASE A2 FROM Bothrops erythromelas VENOM
Provedor de dados: 79
Autores: Prado-Franceschi,J.; Flores,C.A.; Moreno,S.E.; Cogo,J.C.; Hyslop,S.; Giglio,J.R.; Bloch Jr.,C.; Morhy,L.
Tipo: Info:eu-repo/semantics/other
Ano: 1997
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301997000200011