Consulta: creatorFacets:"Kamal,Zul"
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Data/hora: 04/06/2024 11:11:04

Anticholinesterse and antioxidant investigations of crude extracts, subsequent fractions, saponins and flavonoids of atriplex laciniata L.: potential effectiveness in Alzheimer's and other neurological disorders
Provedor de dados: Biological Research
Autores: Kamal,Zul; Ullah,Farhat; Ayaz,Muhammad; Sadiq,Abdul; Ahmad,Sajjad; Zeb,Anwar; Hussain,Abid; Imran,Muhammad.
BACKGROUND: Atriplex laciniata L. was investigated for phenolic, flavonoid contents, antioxidant, anticholinesterase activities, in an attempt to explore its effectiveness in Alzheimer's and other neurological disorders. Plant crude methanolic extract (Al.MeF), subsequent fractions; n-hexane (Al.HxF), chloroform (Al.CfF), ethyl acetate (Al.EaF), aqueous (Al.WtF), Saponins (Al.SPF) and Flavonoids (Al.FLVF) were investigated for DPPH, ABTS and H2O2 free radical scavenging activities. Further these extracts were subjected to acetylcholinesterase (AChE) &amp;amp; butyrylcholinesterase (BChE) inhibitory activities using Ellman's assay. Phenolic and Flavonoid contents were determined and expressed in mg Gallic acid GAE/g and Rutin RTE/g of samples respectively....
Tipo: Journal article
Palavras-chave: Phenolic &amp;amp; Flavonoid contents DPPH ABTS H2O2 Gallic acid IC50 and anticholinesterase.
Ano: 2015
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100021