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Cytotoxic Effect on Cancerous Cell Lines by Biologically Synthesized Silver Nanoparticles
Provedor de dados: 52
Autores: Kulandaivelu,Balaji; Gothandam,K M.
The biosynthesis of nanoparticles has been proposed as an environmental friendly and cost effective alternative to chemical and physical methods. Silver nanoparticles are biologically synthesized and characterized were used in the study. The invitro cytotoxic effect of biologically synthesized silver nanoparticles against MCF-7 cancer cell lines were assessed. The cytotoxic effects of the silver nanoparticles could significantly inhibited MCF-7 cancer cell lines proliferation in a time and concentration-dependent manner by MTT assay. Acridine orange, ethidium bromide (AO/EB) dual staining, caspase-3 and DNA fragmentation assays were carried out using various concentrations of silver nanoparticles ranging from 1 to 100 μg/mL. At 100 μg/mL concentration, the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Silver nanoparticle; Nanotechnology; Nanobiotechnology; Nanoparticle; Cytotoxicity.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100307