Consulta: creatorFacets:"LIMA,LUCIANA A.R.S."
Registros recuperados: 3
Data/hora: 29/05/2024 03:43:19

Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils
Provedor de dados: Anais da Academia Brasileira de Ciências
Autores: PINTO,MARIA E.A.; ARAÚJO,STHÉFANE G.; MORAIS,MARCELA I.; SÁ,NÍVEA P.; LIMA,CAROLINE M.; ROSA,CARLOS A.; SIQUEIRA,EZEQUIAS P.; JOHANN,SUSANA; LIMA,LUCIANA A.R.S.
ABSTRACT Fatty acid methyl esters (FAMEs) were obtained from vegetable oils of soybean, corn and sunflower. The current study was focused on evaluating the antifungal activity of FAMEs mainly against Paracoccidioides spp., as well as testing the interaction of these compounds with commercial antifungal drugs and also their antioxidant potential. FAMEs presented small IC50 values (1.86-9.42 μg/mL). All three FAMEs tested showed antifungal activity against isolates of Paracoccidioides spp. with MIC values ranging from 15.6-500 µg/mL. Sunflower FAMEs exhibited antifungal activity that extended also to other genera, with an MIC of 15.6 μg/mL against Candida glabrata and C. krusei and 31.2 μg/mL against C. parapsilosis. FAMEs exhibited a synergetic effect with...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antifungal; Antioxidant; Fatty acid methyl esters; Vegetable oils.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000401671

Antibacterial activity of Lamiaceae plant extracts in clinical isolates of multidrug-resistant bacteria
Provedor de dados: Anais da Academia Brasileira de Ciências
Autores: ASSIS,FELIPE V. DE; SIQUEIRA,FLÁVIA L.; GONÇALVES,ISABELA E.; LACERDA,RAFAEL P.; NASCIMENTO,RAFAELA A.; ARAÚJO,STHÉFANE G.; ANDRADE,JÉSSICA T.; HERRERA,KARINA M.S.; LIMA,LUCIANA A.R.S.; FERREIRA,JAQUELINE M.S.
ABSTRACT The antibacterial activity of plant extracts of the Lamiaceae family was evaluated against clinical isolates of multi-resistant Gram-negative bacteria by broth microdilution technique. Promising results were obtained considering that all extracts were active for at least two bacterial species with MIC ranging from 0.5 to 2.0 mg/mL.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antibacterial; Clinical isolates; Lamiaceae extracts; Multidrug-resistant.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000401665

In vitro cytotoxic, antifungal, trypanocidal and leishmanicidal activities of acetogenins isolated from Annona cornifolia A. St. -Hil. (Annonaceae)
Provedor de dados: Anais da Academia Brasileira de Ciências
Autores: LIMA,LUCIANA A.R.S.; ALVES,TÂNIA M.A.; ZANI,CARLOS L.; SALES JÚNIOR,POLICARPO A.; ROMANHA,ALVARO J.; JOHANN,SUSANA; CISALPINO,PATRÍCIA S.; PIMENTA,LÚCIA P.S.; BOAVENTURA,MARIA AMÉLIA D.
Annona cornifolia A. St. -Hil. is a small annual perennial tree found in the Brazilian savannah; their green fruit is popularly used in the treatment of ulcers. The acetogenins isolated from the seeds of Annona cornifolia previously showed to possess antioxidant activity. In continuation of our investigations on the biological activities of acetogenins, four binary mixtures and ten pure adjacent bis-tetrahydrofuran annonaceous acetogenins were evaluated: the cytotoxic (against three human tumor cell lines), antifungal (against Paracoccidioides brasiliensis), trypanocidal (against Trypanosoma cruzi) and leishmanicidal (against Leishmania amazonensis) activities. Acetogenins presented cytotoxic activity confirming their potential use in anti-cancer therapy....
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Annona cornifolia; Acetogenins; Cytotoxic; Antifungal; Trypanocidal; Leishmanicidal.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000200829