Consulta: creatorFacets:"LIRA,EDUARDO C."
Registros recuperados: 2
Data/hora: 04/06/2024 06:24:02

Phytochemical Screening and Acute Toxicity of Aqueous Extract of Leaves of Conocarpus erectus Linnaeus in Swiss Albino Mice
Provedor de dados: 42
Autores: NASCIMENTO,DAYANE K.D.; SOUZA,IVONE A. DE; OLIVEIRA,ANTÔNIO F.M. DE; BARBOSA,MARIANA O.; SANTANA,MARLLON A.N.; PEREIRA JÚNIOR,DANIEL F.; LIRA,EDUARDO C.; VIEIRA,JEYMESSON R.C.
ABSTRACT Mangroves represent areas of high biological productivity and it is a region rich in bioactive substances used in medicine production. Conocarpus erectus (Combretaceae) known as button mangrove is one of the species found in mangroves and it is used in folk medicine in the treatment of anemia, catarrh, conjunctivitis, diabetes, diarrhea, fever, gonorrhea, headache, hemorrhage, orchitis, rash, bumps and syphilis. The present study aimed to investigate the acute toxicity of aqueous extract of leaves of C. erectus in Swiss albino mice. The plant material was collected in Vila Velha mangroves, located in Itamaracá (PE). The material was subjected to a phytochemical screening where extractive protocols to identify majority molecules present in leaves...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Acute toxicity; Aqueous extract; Conocarpus erectus; Medicinal plants; Plants extracts.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000401431

Acute Toxicity and Cytotoxicity Effect of Ethanolic Extract of Spondias tuberosa Arruda Bark: Hematological, Biochemical and Histopathological Evaluation
Provedor de dados: 42
Autores: BARBOSA,HUMBERTO M.; NASCIMENTO,JAILSON N. DO; ARAÚJO,THIAGO A.S.; DUARTE,FILIPE S.; ALBUQUERQUE,ULYSSES P.; VIEIRA,JEYMESSON R.C.; SANTANA,EDSON R.B. DE; YARA,RICARDO; LIMA,CLÁUDIA S.A.; GOMES,DAYANE A.; LIRA,EDUARDO C.
ABSTRACT Spondias tuberosa Arruda, popularly named as umbu, is native from savanna-like vegetation and widely used for medicinal purposes, however, the toxicological profile is not available yet. This study evaluated the phytochemical profile and acute toxicity and citoxicity of Ethanolic Extract of Spondias tuberosa Arruda Bark (EEStb) in hematological, biochemical and histopathological parameters. Female Wistar rats were divided into: control (C) and animal treated single doses of 300mg/Kg (EEStb300) or 2.000mg/kg body weight (ESStb2.000) of the EEStb. After 24 hours and 14 days from gavage, the behavior, hematological, biochemical and histopathological parameters were assayed. Cytotoxicity effect was evaluated on HEp-2 cell lines. Neither EEStb300 nor...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Acute toxicity; Cytotoxicity; Phytomedicine; Safety; Spondias tuberosa Arruda; Toxicology.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000501993