Consulta: creatorFacets:"Lavalle,G.E."
Registros recuperados: 18
Data/hora: 09/06/2024 13:55:47

Punção aspirativa por agulha fina para diagnóstico de mastocitoma em cães
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Lavalle,G.E.; Araújo,R.B.; Carneiro,R.A.; Pereira,L.C.
Fine needle aspiration (FNA) associated with the cytological diagnosis mast cell tumor is a widely employed technique in human medicine, but it is still underused in veterinary medicine. The aim of this study was to demonstrate the efficacy of FNA technique for the diagnosis of mast cell tumors in dogs. Over one year period all dogs referred to the Veterinary Hospital of the Universidade Federal de Minas Gerais with tumor-like formations of the skin were submitted to FNA. In order to detect metastasis, both skin lesions and the regional lymph nodes were subjected to FNA. After surgical removal of the lesions, histological examination indicated a complete agreement with the cytological diagnosis. In conclusion, FNA technique is a good choice for diagnosis...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cão; Mastocitoma; Citologia.
Ano: 2003
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352003000400017

Histoplasmose cutânea em gato: relato de caso
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Carneiro,R.A.; Lavalle,G.E.; Araújo,R.B.
Descreve-se um caso de histoplasmose cutânea em um gato, da raça Siamesa, com três anos de idade. O animal apresentava crescimento de aspecto esponjoso, sangüinolento, com secreção purulenta na região nasal, cuja evolução ocorreu em cerca de dois meses. O exame citológico revelou presença de Histoplasma capsulatum. O animal foi tratado com cetoconazol durante 20 dias, ocorrendo remissão completa dos sintomas.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Gato; Histoplasmose; Citologia.
Ano: 2005
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352005000800005

Anastomose cólon-trígono vesical em cães
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Pereira,L.C.; Araújo,R.B.; Gheller,V.A.; Candian,L.S.; Lavalle,G.E.; Malta,M.C.C.; Oliveira,P.P.
Realizou-se anastomose cólon-trígono vesical em 12 cães adultos (cinco machos e sete fêmeas), sem raça definida e clinicamente normais. Todos os animais mantiveram a continência urinária imediatamente após a cirurgia. Amostras da região de transição cólon-trígono vesical foram colhidas aos 30 e 60 dias após a cirurgia para exames histopatológicos. Observou-se infiltrado inflamatório mononuclear na região de anastomose com invasão do epitélio de transição da bexiga sobre a mucosa do fragmento intestinal. A técnica mostrou-se simples e eficiente para a reparação da bexiga, com o cólon funcionando como substituto da bexiga, preservando as funções renal e vesical.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cão; Anastomose cólon-trígono vesical; Bexiga.
Ano: 2002
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352002000400010

Serum evaluation of leptin, IL-6, IGF-1 and estrogen in obese bitches with early stages of mammary carcinoma
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Teixeira,S.V.; Silva,I.L.D.; Nunes,F.C.; Campos,C.B.; Oliveira,M.R.; Lavalle,G.E.; Cassali,G.D.
ABSTRACT The aim of this study was to relate the serum concentration IL-6, IGF-1, leptin and estrogen in non-castrated bitches with or without overweight and early stage mammary carcinomas. Forty-three bitches were divided into four groups, two groups without mammary carcinomas with and without overweight, and two groups with mammary carcinomas with and without overweight. Overweight bitches, with or without mammary carcinomas, were statistically different from bitches by ideal weight, in relation to ECC, IMCC and body fat percentages (P&lt; 0.0001). There was a positive correlation between ECC and IMCC (P&lt; 0.0001), ECC and % GC (P&lt; 0.0001), and IMCC and % GC (P&lt; 0.0001). A positive correlation was found between serum leptin and IL-6 (P= 0.0451)...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Bitches; Obesity; Overweight; Mammary carcinomas; Stage.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000100143

Sarcoma sinovial extra-articular em cão
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: França,S.A.; Serakides,R.; Silva,A.E.; Rachid,M.A.; Moraes,J.R.C.; Lavalle,G.E.; Ocarino,N.M.
One four-year-old, female, Collie, dog presented subcutaneous enlarged mass at the lateral aspect of the left hindlimb, close to the knee joint. Based on the anatomopathological and immunohistochemical findings it was confirmed the diagnosis of extra-articular bifasic synovial sarcoma - grade II.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cão; Neoplasia; Sarcoma sinovial; Imunoistoquímica.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352004000500019

Evaluation of adjuvant chemotherapy in feline injection site-associated sarcoma
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Pereira,S.T.; Campos,C.B.; Horta,R.S.; Lavalle,G.E.; Araujo,R.B.
ABSTRACT Feline Injection Site-Associated Sarcoma (FISS) is a neoplasm that implies in reduction of quality of life and overall survival in feline patients. A retrospective study of 13 cases of FISS was conducted to evaluate the efficacy of surgical treatment associated to chemotherapy with doxorubicin or carboplatin. Local recurrence occurred in all patients. Patients treated with surgery and chemotherapy presented a longer overall survival and disease-free interval when compared to those that solely received surgical treatment, although no statistical significance was observed (p= 0.3360 and 0.7506, respectively). Surgery remains as the main option for FISS treatment. Further prospective studies with larger samples are warranted to investigate the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: FISS; Doxorubicin; Carboplatin; Surgery.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000601508

Epidemiological, clinical and pathological evaluation of overall survival in canines with mammary neoplasms
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Nunes,F.C.; Campos,C.B.; Teixeira,S.V.; Bertagnolli,A.C.; Lavalle,G.E.; Cassali,G.D.
ABSTRACT Canine mammary neoplasms (CMNs) are the most frequent lesions and in female dogs. However, studies correlating pathological criteria with clinical evolution in female dogs with mammary neoplasms are scarce. The present study aims to present epidemiological, clinical-pathological and overall survival data to help establish the prognosis and understand the biological behavior of CMNs. A total of 1539 cases were included (85% malignant and 13% benign). Tumor size was an important prognostic factor and was associated with overall patient survival (P&lt; 0.0001). Most dogs diagnosed with malignant neoplasms (83%) had initial clinical staging, although 17% had regional or distant metastases at the time of diagnosis and lower overall survival (P&lt;...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Female dogs; Mammary gland; Carcinomas; Prognosis.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000601714

Metastatic well differentiated squamous cell carcinoma in the prepuce of a dog: a report of clinicopathological, immunophenotypic and therapeutic approach
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Auler,P.A.; Gamba,C.O.; Horta,R.S.; Lavalle,G.E.; Cassali,G.D.
This report describes a case of a well differentiated squamous cell carcinoma (SCC) of the foreskin of a dog, with metastasis in the regional lymph node. A six-year-old male intact Pit Bull dog presented a preputial ulcerated lesion with an evolution time of one year and enlarged left inguinal lymph node. Surgical resection of the preputial lesion and inguinal lymph nodes was made. The diagnosis of a well differentiated SCC was made following histopathological analysis and immunohistochemistry technique was used to confirm lymph node metastasis and to determine the histological features of the tumor. Here we demonstrated that immunohistochemistry can be an important complementary diagnostic tool to assess the prognostic features of SCC and to determine the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Metastasis; Tumor; Skin; Immunohistochemistry; Chemotherapy.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352014000501317

Ciclooxygenase inhibitor and metronomic chemotherapy association for the treatment of metastatic anal sac carcinoma in dog: case report
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Teixeira,N.C.T.; Bicalho,A.P.C.V.; Vasconcelos,A.V.; Horta,R.S.; Cunha,R.M.C.; Lavalle,G.E.
ABSTRACT Metronomic chemotherapy consists of an anticancer modality treatment. It is applicable in patients at an advanced stage, with the objective of increasing overall survival. The aim of this study was to report an anal sac apocrine carcinoma case in a dog with lymph node metastasis treated with metronomic chemotherapy sequential to surgery and conventional chemotherapy using gemcitabine and carboplatin. Metronomic chemotherapy was associated with cyclooxygenase-2 (COX-2) inhibitors, due to strong tumor COX-2 immunohistochemistry expression. Metronomic chemotherapy was initiated with cyclophosphamide, but it was replaced by lomustine, also in metronomic dosage, due to adverse effects. Treatment showed effectiveness, since the patient's overall...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Dog; Oncology; Angiogenesis inhibitor; Cyclophosphamide; Lomustine.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000400913

Hepatic cirrhosis in a red-foot tortoise (Geochelone carbonaria): a case report
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Guedes,R.M.C.; Lavalle,G.E.
Um jabuti (Geochelone carbonaria) de 30 anos de idade foi encaminhado ao setor de patologia para exame post mortem. À necropsia, foi observada ascite acentuada. O fígado apresentava-se diminuído de volume e com vários nódulos firmes entre 0.3 e 1.0 cm de diâmetro distribuídos por todo o órgão. À microscopia, esses nódulos eram constituídos externamente por espessa camada de tecido conjuntivo fibroso envolvendo hepatócitos dilatados e vacuolizados na sua porção central. A cirrose conseqüente à lipidose hepática foi provavelmente causada por níveis baixos de proteína na dieta.
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Red-foot tortoise; Geochelone carbonaria; Liver cirrhosis.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352004000100020

Assessment of electrochemotherapy effects on the development of Ehrlich solid tumor in swiss mice using a novel electroporator device
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Cunha,R.M.C.; Lavalle,G.E.; Reis,D.C.; Horta,R.S.; Teixeira,S.V.; Ramirez,J.A.; Araújo,R.B.
ABSTRACT Electrochemotherapy is a local anticancer treatment in which non-permeant chemotherapeutic drugs are associated with electric pulses of well-established parameters. The electric pulses cause pores to open on the plasma membrane and facilitate drug transport, enhancing cytotoxicity and reducing side effects. Assessment of electrochemotherapy effects on Ehrlich solid tumor development in this work aims to evaluate in vivo usage of the electroporator device developed by the Department of Electrical Engineering of Engineering School of UFMG. Therefore, 40 Swiss mice were inoculated with Ehrlich tumor cells, and developed the tumor in solid form. After 21 days, mice were subjected to specific treatment protocols (control, bleomycin, electric pulses and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Mouse; Oncology; Electrochemotherapy; Experimental tumor.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000601581

Leiomiossarcoma pulmonar e renal em cão: relato de caso
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Serakides,R.; Sant’Ana,F.J.F.; Carneiro,R.A.; Lavalle,G.E.
Este relato descreve um caso de leiomiossarcoma pulmonar e renal em cão da raça Husky Siberiano, macho, de nove anos de idade e com histórico de emagrecimento progressivo há mais de três meses. Ao exame clínico, o animal apresentava palidez discreta das mucosas e dor intensa à palpação abdominal, além de aumento de volume acentuado dos rins. No hemograma, foi evidenciada anemia discreta e na urinálise foram observados isostenúria e grumos de células do epitélio renal. Os níveis plasmáticos de uréia e creatinina estavam dentro dos limites considerados normais. O animal foi sacrificado após a confirmação de neoplasia renal bilateral por laparotomia exploratória. À necropsia, os rins apresentavam vários nódulos de 0,5 a 4cm de diâmetro, esbranquiçados e...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cão; Rins; Pulmões; Leiomiossarcoma; Imuno-histoquímica.
Ano: 2000
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352000000600008

Lipossarcoma em cão: relato de dois casos
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Sant'Ana,F.J.F.; Serakides,R.; Lavalle,G.E.
This work aims to describe the clinical and anatomopathological findings of two cases of liposarcoma diagnosed in the subcutaneous and abdominal cavity of dogs. In both cases, the tumoral masses were surgically removed and samples were submitted for histopathological analyses. Microscopic examination of each case revealed a highly cellular, pleomorphic neoplasm with round or polygonal fat cells. The nuclei was elongate or splindle-shape (subcutaneous liposarcoma) and round or ovoid (abdominal liposarcoma), contained margined chromatin, and prominent nucleolus. Cytoplasmic vacuoles that stained positively with Sudan IV varied highly in size.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cão; Lipossarcoma subcutâneo; Lipossarcoma abdominal.
Ano: 2003
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352003000100020

Subcutaneous administration of ketoprofen delays Ehrlich solid tumor growth in mice
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Souza,C.M.; Auler,P.A.; Reis,D.C.; Lavalle,G.E.; Ferreira,E.; Cassali,G.D.
Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID) has proven to exert anti-inflammatory, anti-proliferative and anti-angiogenic activities in both neoplastic and non-neoplastic conditions. We investigated the effects of this compound on tumor development in Swiss mice previously inoculated with Ehrlich tumor cells. To carry out this study the solid tumor was obtained from cells of the ascites fluid of Ehrlich tumor re-suspended in physiological saline to give 2.5x106cells in 0.05mL. After tumor inoculation, the animals were separated into two groups (n = 10). The animals treated with ketoprofen 0.1µg/100µL/animal were injected intraperitoneally at intervals of 24h for 10 consecutive days. Animals from the control group received saline. At the end...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Inflammation; Cell proliferation; Ketoprofen; Neoplasm.
Ano: 2014
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352014000501376

Tumor maligno da bainha de nervo periférico em cães: relato de três casos
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Silva,C.M.O.; Caldeira,F.M.C.; Melo,E.G.; Ocarino,N.M.; Silva,A.E.; Guedes,R.M.C.; Lavalle,G.E.; Serakides,R.
Descrevem-se os achados anatomoclínicos e imunoistoquímicos dos tumores da bainha de nervos periféricos em três cães atendidos em hospital. Os animais apresentavam sintomatologia variável de acordo com a localização do tumor. À microscopia, as neoplasias eram invasivas e constituídas por células pleomórficas e anaplásicas que variavam de poligonais a fusiformes, arranjadas em padrão sólido difuso, por vezes em paliçada. Foi firmado o diagnóstico de tumor da bainha de nervos periféricos nos três casos.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cão; Tumor da bainha de nervos periféricos; Imunoistoquímica.
Ano: 2007
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352007000300020

Clinical and pathological aspects of multicentric hemangiosarcoma in a Pinscher dog
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Martins,B.D.C.; Torres,B.B.J.; Rodriguez,A.A.M.; Gamba,C.O.; Cassali,G.D.; Lavalle,G.E.; Martins,G.D.C.; Melo,E.G.
A 3-year-old female Pinscher dog was presented with a history of lameness and pain in hind limbs for one week which acutely progressed to non-ambulatory paraparesis. The dog had been apathetic and anorexic during the six days prior to presentation. The neurological findings were compatible with upper motor neuron signs to the left hind limb due to a spinal cord compressive mass on the twelfth thoracic vertebral body. On the other hand, signs of lower motor neurons to the right hind limb were due to a mass with a pathological fracture in the right proximal femur, compressing the sciatic nerve. A histopathological analysis of all organs revealedthe proliferation of endothelial cells showingin filtrative growth and organization into vascular structures with a...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Dog; Neuropathy; Hemangiosarcoma; CD-31; Immunohistochemistry.
Ano: 2013
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000200003

Glycogen-rich clear cell carcinoma of the feline mammary gland: case report
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Campos,C.B.; Gamba,C.O.; Damasceno,K.A.; Lavalle,G.E.; Cassali,G.D.
ABSTRACT The aim of this report is to describe the first histopathological, immunohistochemical, and clinical characteristics of a feline glycogen-rich clear cell carcinoma (GRCCC). A Persian queen was admitted with mammary gland tumors and underwent radical unilateral mastectomy. Overall survival was considered 33 days and death was due to clinical evolution of the disease. Microscopic evaluation demonstrated epithelial cells arranged in a predominantly solid pattern, tumor cells presented an ample, granular, and foamy clear cytoplasm, and moderate cellular pleomorfism. The presence of cytoplasmatic glycogen was confirmed through diastase digestion followed by PAS staining. Histopathological and histochemical findings lead to the diagnosis of GRCCC with...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Feline; Mammary gland; Neoplasm; Glycogen-rich clear cell carcinoma.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000501117

Outcome of adjuvant chemotherapy with lomustine, vinblastine and chlorambucil on management of canine mast cell tumour of high to intermediate risk
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Horta,R.S.; Lavalle,G.E.; Costa,M.P.; Moura,L.L.; Marcinowska,A.; Araújo,R.B.
ABSTRACT In spite of the many available protocols, the use of chemotherapy for the management of canine mast cell tumours (MCT) remains empirical, and there is lack of criteria for the choice of protocol and definition of patients who may benefit from treatment. The objective of this study was to evaluate the outcome of dogs with MCT after adjuvant chemotherapy according to the risk of recurrence or metastasis proposed on the literature. This prospective study included 89 followed up dogs with prognosis assesment including clinical, histological, immunohistochemical and genetic features of canine MCT. Patients were grouped according to risk of recurrence and metastasis and recommended treatment with lomustine followed by chlorambucil if considered at...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Dog; Neoplasm; Mast cells; Ki-67; C-kit.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000601426