Consulta: creatorFacets:"Le Foll, Frank"
Registros recuperados: 1
Data/hora: 09/06/2024 09:32:05

Infection dynamics of a V. splendidus strain pathogenic to Mytilus edulis : In vivo and in vitro interactions with hemocytes
Provedor de dados: Institutional Archive of Ifreme (ArchiMer)
Autores: Ben Cheikh, Yosra; Travers, Marie-agnes; Le Foll, Frank.
The pathogenic strain V. splendidus 10/068 1T1 has previously been reported for its virulence to the blue mussel and for its capacity to alter immune responses. In this study, we expanded the knowledge on hemocyte-pathogen interactions by using in vitro and in vivo assays. V. splendidus 10/068 1T1 severely inhibited cell adhesion and acidic vacuole formation unlike the innocuous phylogenetically related V. splendidus 12/056 M24T1 which had no effect on these cell functions. Furthermore, the virulent bacteria decreased hemocyte viability (59% of viability after 24 h). Infection dynamics were explored by using a model based on water tank cohabitation with septic mussels infected by GFP-tagged V. splendidus 10/068 1T1. Experimental infections were...
Tipo: Text
Palavras-chave: Innate immunity; Bivalves; Vibrio; Infection; Experimental model; Hemocyte.
Ano: 2017
URL: http://archimer.ifremer.fr/doc/00400/51136/53772.pdf