Consulta: creatorFacets:"Li,Dan"
Registros recuperados: 3
Data/hora: 13/06/2024 04:28:20

Antimicrobial susceptibility, virulence determinant carriage and molecular characteristics of Staphylococcus aureus isolates associated with skin and soft tissue infections
Provedor de dados: 55
Autores: Yu,Fangyou; Liu,Yunling; Lv,Jinnan; Qi,Xiuqin; Lu,Chaohui; Ding,Yu; Li,Dan; Liu,Huanle; Wang,Liangxing.
ABSTRACT A better understanding of the antimicrobial susceptibility, carriage of virulence determinants and molecular characteristics of Staphylococcus aureus isolates associated with skin and soft tissue infections (SSTIs) may provide further insights related to clinical outcomes with these infections. From January 2012 to September 2013, a total of 128 non-duplicateS. aureus isolates were recovered from patients with SSTIs. All 128 S. aureus SSTI isolates carried at least five virulence genes tested. Virulence genes detected among at least 70% of all tested isolates included hld (100%), hla (95.3%),icaA (96.9%), clf (99.2%),sdrC (79.7%), sdrD (70.3%), andsdrE (72.7%). The prevalence of MRSA isolates with 10 virulence genes tested (54.4%, 31/56) was...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Staphylococcus aureus; Skin and soft tissue infections; Molecular characteristic; Virulence genes.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000600614

The carriage of the serine-aspartate repeat protein-encodingsdr genes among Staphylococcus aureuslineages
Provedor de dados: 55
Autores: Liu,Huanle; Lv,Jingnan; Qi,Xiuqin; Ding,Yu; Li,Dan; Hu,Longhua; Wang,Liangxing; Yu,Fangyou.
ABSTRACTThe serine-aspartate repeat proteins (Sdr) are members of a family of surface proteins and contribute to the pathogenicity of Staphylococcus aureus. Among 288 S. aureus isolates including 158 and 130 associated with skin and soft tissue infections and bloodstream infection, respectively; 275 (95.5%) were positive for at least one of threesdr genes tested. The positivity rates for sdrC, sdrD, and sdrE among S. aureusisolates were 87.8% (253/288), 63.9% (184/288), and 68.1% (196/288), respectively. 224 (77.8%) of 288 isolates were concomitantly positive for two or three sdr genes. There was an association between carriage ofsdrE and methicillin-resistant S. aureus(MRSA) isolates, while the carriage rates of sdrC andsdrD in MRSA isolates were similar...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Staphylococcus aureus; Sdr genes; Clonal lineages.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000500498

Comparative proteomics analysis of chronic atrophic gastritis: changes of protein expression in chronic atrophic gastritis without Helicobacter pylori infection
Provedor de dados: 56
Autores: Zhang,Lin; Hou,Yanhong; Wu,Kai; Li,Dan.
Chronic atrophic gastritis (CAG) is a very common gastritis and one of the major precursor lesions of gastric cancer, one of the most common cancers worldwide. The molecular mechanism underlying CAG is unclear, but its elucidation is essential for the prevention and early detection of gastric cancer and appropriate intervention. A combination of two-dimensional gel electrophoresis and mass spectrometry was used in the present study to analyze the differentially expressed proteins. Samples from 21 patients (9 females and 12 males; mean age: 61.8 years) were used. We identified 18 differentially expressed proteins in CAG compared with matched normal mucosa. Eight proteins were up-regulated and 10 down-regulated in CAG when compared with the same amounts of...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Differentially expressed proteins; Chronic atrophic gastritis; Proteomic study; Ribosomal protein S12 (RPS12); Proteasome activator subunit 1 (PSME1).
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000300014