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Achyrocline satureioides (Lam.) DC. (marcela) reduces brain damage in permanent focal ischemia in rats
Provedor de dados: 98
Autores: Rivera Megret,Felicia; Tejera Correa,Dario; Abin Carriquiri,Juan Andrés; Prunell dos Santos,Giselle; Martínez Busi,Marcela; Dajas Méndez,Federico.
Introduction: Achyrocline satureioides is a plant which has been widely used in popular medicine and experimental studies confirm its antioxidant and anti-inflammatory effects, attributable to the presence of flavonoids, mainly quercetin. Objectives: to evaluate the neuroprotective effects of a chronic oral pre-administration to rats with an Achyrocline satureioides decoction (2 %). Methods: for decoction, dried flowers of Achyrocline satureioides were used. The consumption of food and AS decoction/water of the rats was evaluated daily and weight gain weekly; quercetin content in the decoction and in the plasma of the rats was evaluated by high performance liquid chromatography. The cerebral damage was assessed with a tetrazolium salt (TTC) and a...
Tipo: Journal article
Palavras-chave: Achyroclines satureioides; Quercetin; Permanent focal ischemia.
Ano: 2013
URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1028-47962013000300011