Consulta: creatorFacets:"Menaldo,Danilo Luccas"
Registros recuperados: 1
Data/hora: 08/06/2024 05:32:19

Immunotherapeutic potential of Crotoxin: anti-inflammatory and immunosuppressive properties
Provedor de dados: 80
Autores: Sartim,Marco Aurélio; Menaldo,Danilo Luccas; Sampaio,Suely Vilela.
Abstract For the past 80 years, Crotoxin has become one of the most investigated isolated toxins from snake venoms, partially due to its major role as the main toxic component in the venom of the South American rattlesnake Crotalus durissus terrificus. However, in the past decades, progressive studies have led researchers to shift their focus on Crotoxin, opening novel perspectives and applications as a therapeutic approach. Although this toxin acts on a wide variety of biological events, the modulation of immune responses is considered as one of its most relevant behaviors. Therefore, the present review describes the scientific investigations on the capacity of Crotoxin to modulate anti-inflammatory and immunosuppressive responses, and its application as...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Crotalus durissus terrificus; Crotoxin; Innate immunity; Adaptative immunity; Inflammation.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992018000100329