Consulta: creatorFacets:"Mesa-Junior,C.O."
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Data/hora: 16/06/2024 00:42:38

Effect of 30 mCi radioiodine on multinodular goiter previously treated with recombinant human thyroid-stimulating hormone
Provedor de dados: 56
Autores: Paz-Filho,G.J.; Mesa-Junior,C.O.; Olandoski,M.; Woellner,L.C.; Goedert,C.A.; Boguszewski,C.L.; Carvalho,G.A.; Graf,H.
Recombinant human thyroid-stimulating hormone (rhTSH) enhances 131I uptake, permitting a decrease in radiation for the treatment of multinodular goiter (MNG). Our objective was to evaluate the safety and efficacy of a single 0.1-mg dose of rhTSH, followed by 30 mCi 131I, in patients with MNG. Seventeen patients (15 females, 59.0 ± 13.1 years), who had never been submitted to 131I therapy, received a single 0.1-mg injection of rhTSH followed by 30 mCi 131I on the next day. Mean basal thyroid volume measured by computed tomography was 106.1 ± 64.4 mL. 131I 24-h uptake, TSH, free-T4, T3, thyroglobulin, anti-thyroid antibodies, and thyroid volume were evaluated at regular intervals of 12 months. Mean 131I 24-h uptake increased from 18.1 ± 9.7 to 49.6 ± 13.4%...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Multinodular goiter; Thyroid; Recombinant TSH; Radioiodine; 131I.
Ano: 2007
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007001200010