Consulta: creatorFacets:"Metze,K."
Registros recuperados: 4
Data/hora: 08/06/2024 09:43:37

Clinical utility of a life quality score in dogs with canine transmissible venereal tumor treated by vincristine chemotherapy
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Valladão,M.L.; Scarpelli,K.C.; Metze,K.
The clinical utility of a life quality score during vincristine chemotherapy of dogs with canine transmissible venereal tumor (CTVT) was investigated using 93 tumor-bearing dogs in this prospective study. At diagnosis, clinical data and the performance status were evaluated according to a modified Karnofsky score (CKS) adapted for dogs. The animals were treated with vincristine sulphate (0.025mg/kg) at weekly intervals until the tumor had macroscopically disappeared. The time until the first adverse event and death were recorded. In a pilot study, CKS revealed a high inter-observer concordance (kappa=0.735; weighted kappa=0.835). CKS permitted a detailed monitoring of adverse effects during therapy. Cox regressions showed that low performance score and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Canine transmissible venereal tumor; Vincristine; Survival; Performance score; Quality of life.
Ano: 2010
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352010000500010

Comments on the paper "c-erbB-2 expression and nuclear pleomorphism in canine mammary tumors"
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Metze,K.; Adam,R.L.
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Canine mammary tumors; Nuclear pleomorphism; Statistical analysis; Scientific methods; C-erbB-2 expression; MIB-1 expression.
Ano: 2005
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000200001

Immunoexpression of CD95 in chronic gastritis and gastric mucosa-associated lymphomas
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Vassallo,J.; Godoy Jr.,C.E.; Godoy,C.E.; Chagas,C.A.; Metze,K.; Trevisan,M.A.S.
CD95 (Fas/APO-1)-mediated apoptosis plays an important role in immunological regulation and is related to the pathogenesis of autoimmune diseases. Immunoexpression of CD95 has been reported to frequently occur in low grade non-Hodgkin lymphomas, especially of post-germinal center histogenesis, among which those originating in mucosa-associated lymphoid tissue (MALT lymphomas). However, there is no report comparing in situ immunoexpression of this marker in lymphomas and the hyperplastic lymphoid reaction (chronic gastritis) related to Helicobacter pylori infection. The purpose of the present research was to compare the intensity of lymphoid CD95 immunoexpression in 15 cases of H. pylori-related chronic gastritis and 15 gastric MALT lymphomas. CD95...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: CD95; FAS/APO1; Apoptosis; Chronic gastritis; MALT lymphoma.
Ano: 2004
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000900015

Acute leukemias in Piauí: comparison with features observed in other regions of Brazil
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Rego,M.F.N.; Pinheiro,G.S.; Metze,K.; Lorand-Metze,I.
Differences in age and sex distribution as well as FAB (French-American-British classification) types have been reported for acute leukemias in several countries. We studied the demographics and response to treatment of patients with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) between 1989 and 2000 in Teresina, Piauí, and compared these results with reports from Brazil and other countries. Complete data concerning 345 patients (230 ALL, 115 AML) were reviewed. AML occurred predominantly in adults (77%), with a median age of 34 years, similar to that found in the southeast of Brazil but lower than the median age in the United States and Europe (52 years). FAB distribution was similar in children and adults and FAB-M2 was the most...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Acute lymphoblastic leukemia; Acute myeloid leukemia; Epidemiology.
Ano: 2003
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000300007