Consulta: creatorFacets:"Moraes-Souza,Hélio"
Registros recuperados: 1
Data/hora: 16/06/2024 09:17:38

The application of latent class analysis for diagnostic test validation of chronic Trypanosoma cruzi infection in blood donors
Provedor de dados: 55
Autores: Langhi Junior,Dante M.; Bordin,José O.; Castelo,Adauto; Walter,Stephen D.; Moraes-Souza,Hélio; Stumpf,Robert J.
The main strategy to prevent transfusion-associated Chagas' disease is the identification of T. Cruzi-infected blood donors by serological screening tests, however there is no perfect serological gold standard. We evaluated an enzyme immunoassay (EIA), an indirect hemaglutination (IHA), and an indirect immunofluorescence (IIF) test for detecting T. Cruzi antibodies in Brazilian blood donors. The results were submitted to latent class analysis, and a radioimmunopreciptation (RIPA) test was performed on repeatedly positive samples. Among 1951 donors, 11 (0.56%) were positive by EIA, 6 (0.31%) by IHA and 16 (0.82%) by IIF. Six samples were positive with all tests, while 4 reacted with EIA and IIF. The RIPA was positive in 6 (75.0%), 7 (66.6%), and 4 (54.0%)...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Chaga's disease; Blood donors; Diagnostic test; Latent class analysis.
Ano: 2002
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000400005