Consulta: creatorFacets:"Morrone,Fernanda Bueno"
Registros recuperados: 2
Data/hora: 08/06/2024 14:49:14

Effect of LPS on the Viability and Proliferation of Human Oral and Esophageal Cancer Cell Lines
Provedor de dados: 52
Autores: Gonçalves,Márcia; Cappellari,Ángelica Regina; Santos Junior,André Avelino dos; Marchi,Fernanda Olicheski de; Macchi,Fernanda Souza; Antunes,Krist Helen; Souza,Ana Paula Duarte de; Morrone,Fernanda Bueno.
The esophagus and mouth tumors are very frequent malignancies worldwide. Lipopolysaccharides (LPS) are capable of regulating gene expression of pro-inflammatory cytokines by binding to toll-like receptor 4 (TLR4). Recent studies show that LPS can increase the migration ability of human esophageal cancer cell line HKESC-2 by increasing its adhesion properties. However, the effect of LPS has not been tested on viability of human esophageal and oral cancer cells. This study aimed to determine the action of LPS on the cell proliferation and viability in OE19 (adenocarcinoma) and OE21 (squamous carcinoma) cell lines, representative of human esophageal cancer, and HN30 cell line, representative of human oral carcinoma. LPS was used as treatment to OE19 and OE21...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: LPS; Oral cancer; Esophageal cancer; TLR4.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100306

Potential interactions of central nervous system drugs used in the elderly population
Provedor de dados: 60
Autores: Morrone,Fernanda Bueno; Schroeter,Guilherme; Petitembert,Alessandra P.; Faggiani,Fabiana T.; De Carli,Geraldo Atillio.
OBJECTIVE: To describe the use of CNS drugs and to identify the most frequently observed potential drug interactions in the elderly living in Southern Brazil. METHODS: A population-based, transversal and observational study was carried out during 2006-2007. Four hundred and eighty elderly individuals of both genders were randomly recruited and interviewed. A validated pharmacotherapeutic questionnaire and the Micromedex® Healthcare Series were utilized to analyze potential drug interactions. A severity rating scale employing the categories of "mild", "moderate" and "severe" was used to describe the interactions. RESULTS: A population of elderly living in Southern Brazil was interviewed and 98 reported using CNS drugs, 74.5% female and 25.5% male. Out of...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Elderly; Drug-Drug interactions; Central nervous system; Tobacco; Ethanol.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000200006