Consulta: creatorFacets:"Moura,Alexandre Sampaio"
Registros recuperados: 4
Data/hora: 28/05/2024 16:29:00

Syphilitic meningitis in HIV-patients with meningeal syndrome: report of two cases and review
Provedor de dados: Brazilian Journal of Infectious Diseases
Autores: Carmo,Ricardo Andrade; Moura,Alexandre Sampaio; Christo,Paulo Pereira; Morandi,Ana Cláudia; Oliveira,Marcelo Silva.
Few patients with symptomatic neurosyphilis present with signs and symptoms of acute meningitis. Here we report two cases of syphilitic meningitis diagnosed in HIV patients with meningeal syndrome. The first case, a 30-year-old black bisexual male, had concurrent meningeal and ocular syphilis with persistent unusually low CSF glucose levels. He responded well to 21 days of intravenous penicillin therapy. The second case was a 55-year-old female with epilepsy, depression, behavioral disorder and confusion. The diagnosis of HIV infection was made after onset of the syphilitic meningitis. She was treated with 21 days i.v. penicillin with improvement in her clinical condition. The clinical aspects of combined neurosyphilis and HIV infection, plus special...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: AIDS; Meningitis; Neurosyphilis.
Ano: 2001
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000500007

Clinical management of a patient with drug dependence who attempted suicide while receiving peginterferon therapy for chronic hepatitis C
Provedor de dados: Brazilian Journal of Infectious Diseases
Autores: Fábregas,Bruno Cópio; Moura,Alexandre Sampaio; Marciano,Renata Cristiane; Carmo,Ricardo Andrade; Teixeira,Antônio Lúcio.
Pegylated interferon-alpha combined with ribavirin is the current gold standard treatment for chronic hepatitis C. Illicit drug dependence is not a rare co-morbidity among chronic hepatitis C population, what can make antiviral treatment an outmost challenge. Despite high sustained virological response rate following antiviral treatment, serious psychiatric adverse reactions may occur, like depression and suicide attempt. We report a patient with recurrent depressive disorder, previous history of suicide attempt and illicit drug dependence. We discuss the singularities and challenges of managing this patient in order to complete the antiviral treatment.
Tipo: Info:eu-repo/semantics/report
Palavras-chave: Interferon-alpha; Chronic hepatitis C; Depression; Suicide attempt; Drug addiction.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000500015

Health related quality of life among patients with chronic hepatitis C: a cross-sectional study of sociodemographic, psychopathological and psychiatric determinants
Provedor de dados: Brazilian Journal of Infectious Diseases
Autores: Fábregas,Bruno Cópio; Ávila,Renata Eliane de; Faria,Marjore Novaes; Moura,Alexandre Sampaio; Carmo,Ricardo Andrade; Teixeira,Antonio Lúcio.
INTRODUCTION: Chronic hepatitis C virus infection patients have higher rates of psychiatric disorders than the general population. Chronic hepatitis C virus infection is known to be associated with impaired health related quality of life. To our knowledge, there is no previous research of health related quality of life in chronic hepatitis C patients that combined structured psychiatric interview and careful psychopathological evaluation, including depression, anxiety and fatigue instruments. The aim of this study was to evaluate health related quality of life of chronic hepatitis C patients and to investigate the association with sociodemographic, psychopathological and psychiatric factors. MATERIALS AND METHODS: Eighty-one individuals with chronic...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Quality of life; WHOQOL-BREF; Hepatitis C; Depression; Fatigue.
Ano: 2013
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000600002

Soluble inflammatory markers as predictors of hepatocellular damage and therapeutic response in chronic hepatitis C
Provedor de dados: Brazilian Journal of Infectious Diseases
Autores: Moura,Alexandre Sampaio; Carmo,Ricardo Andrade; Teixeira,Antonio Lucio; Rocha,Manoel Otávio da Costa.
Hepatitis C is an important burden worldwide being an important cause of cirrhosis and liver cancer in different parts of the world. Host immune response, especially T helper type 1 (Th1) cell-mediated, seems to play an important role in disease progression but is also crucial for viral elimination following specific therapy. Immune activation can be evaluated using peripheral levels of different cytokines, such as different chemokines (e.g. CCL5, CXCL10) and tumor necrosis factor alpha (TNF-α), and their soluble receptors (e.g. soluble TNF-α receptors 1 (sTNF-R1) and 2 (sTNF-R2). This review article focuses on the potential use of peripheral inflammatory markers as predictors of liver histological changes and therapeutic response among patients with...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Hepatitis C; Chemokines; Tumor necrosis factor receptor; Interferon-alpha; Liver fibrosis.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000500013