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Antimicrobial, antioxidant and cytotoxicity potential of Manihot multifida (L.) Crantz (Euphorbiaceae)
Provedor de dados: 42
Autores: FABRI,RODRIGO L.; SÁ,DANIEL S. DE; PEREIRA,ANA PATRÍCIA O.; SCIO,ELITA; PIMENTA,DANIEL S.; CHEDIER,LUCIANA M.
Manihot multifida (L.) Crantz (Euphorbiaceae) is widely used in popular medicine for the treatment of infected wounds. This study evaluated thein vitro antioxidant and antimicrobial potential of this species against strains of Gram-positive and Gram-negative bacteria and fungi, known to cause infections in humans. The extracts showed minimal inhibitory concentration (MIC) varying from 39 to 2500 µg/mL for antimicrobial activity. The methanolic extract of fruits, aqueous and hexane extracts of leaves showed a very strong activity against Candida albicans(ATCC 18804) with MIC of 39 µg/mL. Furthermore, the methanolic extract of M. multifida leaves exhibited DPPH (1,1-diphenyl-2-picrylhydrazyl) scavenging potential with inhibitory concentration (IC50) values...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Antimicrobial; Antioxidant; Candida albicans; Cytotoxicity; Manihot multifida.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000100303