Consulta: creatorFacets:"Pereira,V.A.R."
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Data/hora: 10/06/2024 02:57:15

Pros and cons of insulin administration on liver glucose metabolism in strength-trained healthy mice
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Pereira,V.A.R.; Vedovelli,K.S.; Muller,G.Y.; Depieri,Y.F.; Avelar,D.H.C.G.; de Amo,A.H.E.; Jimenes,D.R.; Martins,J.N.L.; Silvério,A.C.; Gomes,C.R.G.; Godoi,V.A.F.; Pedrosa,M.M.D.
Non-diabetic individuals use hormones like insulin to improve muscle strength and performance. However, as insulin also leads the liver and the adipose tissue to an anabolic state, the purpose of this study was to investigate the effects of insulin on liver metabolism in trained non-diabetic Swiss mice. The mice were divided into four groups: sedentary treated with saline (SS) or insulin (SI) and trained treated with saline (TS) or insulin (TI). Training was made in a vertical stair, at 90% of the maximum load, three times per week. Insulin (0.3 U/kg body weight) or saline were given intraperitoneally five times per week. After eight weeks, tissue and blood were collected and in situ liver perfusion with glycerol+lactate or alanine+glutamine (4 mM each)...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Muscle strength; Gluconeogenesis; Liver; Adiposity; Training.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000200605