Consulta: creatorFacets:"Ran,B."
Registros recuperados: 2
Data/hora: 02/06/2024 09:33:29

Estrogen and progesterone promote breast cancer cell proliferation by inducing cyclin G1 expression
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Tian,J-M.; Ran,B.; Zhang,C-L.; Yan,D-M.; LI,X-H.
Breast cancer is the most common cause of cancer among women in most countries (WHO). Ovarian hormone disorder is thought to be associated with breast tumorigenesis. The present study investigated the effects of estrogen and progesterone administration on cell proliferation and underlying mechanisms in breast cancer MCF-7 cells. It was found that a single administration of estradiol (E2) or progesterone increased MCF-7 cell viability in a dose-dependent manner and promoted cell cycle progression by increasing the percentage of cells in the G2/M phase. A combination of E2 and progesterone led to a stronger effect than single treatment. Moreover, cyclin G1 was up-regulated by E2 and/or progesterone in MCF-7 cells. After knockdown of cyclin G1 in MCF-7 cells...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Breast cancer; Estrogen; Progesterone; Cyclin G1; Cell proliferation.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000300611

A morphometric study of the lumbar spinous process in the Chinese population
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Cai,B.; Ran,B.; Li,Q.; Li,Z.H.; Li,F.N.; Li,M.; Yan,W.J.
Our goal was to analyze the anatomical parameters of the lumbar spine spinous process for an interspinous stabilization device designed for the Chinese population and to offer an anatomical basis for its clinical application. The posterior lumbar spines (T12-S1) of 52 adult cadavers were used for measuring the following: distance between two adjacent spinous processes (DB), distance across two adjacent spinous processes (DA), thickness of the central spinous processes (TC), thickness of the superior margin of the spinous processes (TS), thickness of the inferior margin of the spinous processes (TI), and height of the spinous processes (H). Variance and correlation analyses were conducted for these data, and the data met the normal distribution and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Lumbar spine; Morphometry; Spinal stenosis; Spinous process.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000100091