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Evaluation of the Toxicity of Silver/Silica and Titanium Dioxide Particles in Mammalian Cells
Provedor de dados: 52
Autores: Pittol,Michele; Tomacheski,Daiane; Simões,Douglas Naue; Ribeiro,Vanda Ferreira; Santana,Ruth Marlene Campomanes.
ABSTRACT The increasing concern over the spread of diseases has lead to a high consumption of antimicrobial additives in the medical and industrial fields. Since these particles can lixiviate from loaded materials, the contact between this additive and mammalian cells can occur during manufacture, use and disposal of the products. Silver on fumed silica (AgNP_SiO2) and titanium dioxide (TiO2) can be used as antimicrobial additives that are applied in polymeric formulation. While these additives can inhibit bacteria, fungus and virus proliferation; they may also be harmful to humans. Standard toxicological studies were undertaken using the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyltetrazolium bromide), CBPI (cytokinesis-block proliferation index) and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Titanium dioxide; Silver; Silica; Toxicology; Mammalian cell.
Ano: 2018
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100318