Consulta: creatorFacets:"Saito,Felipe Hiroshi"
Registros recuperados: 2
Data/hora: 10/06/2024 10:01:00

Evaluation of cell proliferation and apoptosis in placentas of rats with severe diabetes
Provedor de dados: 52
Autores: Rudge,Marilza Vieira Cunha; Costa,Elaine; Barbisan,Luis Fernando; Damasceno,Débora Cristina; Bueno,Aline; Saito,Felipe Hiroshi; Calderon,Iracema Mattos Paranhos; Rodrigues,Marcela Marcondes Pinto.
The aim of this work was to analyze the cell proliferation and apoptosis indexes on the 18th and 21st days of pregnancy of diabetic rats and to correlate with maternal glycemia and perinatal outcomes. Placentas from 20 Wistar rats were collected and divided into four experimental groups: control and diabetic of 18 and 21 days of pregnancy. The cell proliferation was analyzed using the PCNA expression and apoptosis by the TUNEL method. It was observed that PCNA and TUNEL indexes decreased from day 18 to 21 of pregnancy in the placentas of diabetic rats and these values were lower than control groups. Diabetic dams presented higher percentage of small for pregnancy age (SPA) fetuses. However, there was no difference between the PCNA and TUNEL indexes in SPA...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Diabetes; Cell proliferation; Apoptosis; Placenta; Rat; IUGR.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000200009

Effect of oral supplementation of the linoleic and gammalinolenic acids on the diabetic pregnant rats
Provedor de dados: 52
Autores: Consonni,Marcos; Damasceno,Débora Cristina; Kempinas,Wilma De Grava; Nassr,Azize Cristina Capelli; Volpato,Gustavo Tadeu; Dallaqua,Bruna; Iessi,Isabela Lovizutto; Saito,Felipe Hiroshi; Calderon,Iracema Mattos Paranhos; Rudge,Marilza Vieira Cunha.
The aim of this work was to evaluate the direct protective action of oral fatty acid supplementation against the deleterious effect of hyperglycemia on maternal reproductive outcomes; fetal growth and development on female Wistar rats. The animals were distributed into four experimental groups: G1= non-diabetic without supplementation (Control group); G2= non-diabetic treated with linoleic (LA) and gammalinolenic acid (GLA) (1 mL of Gamaline-V/day); G3= diabetic without supplementation and G4= diabetic treated with LA and GLA. Diabetes was induced by streptozotocin (40 mg/kg). At day 21 of pregnancy, the gravid uterus was weighed and dissected to count the dead and live fetuses, resorption, implantation, and corpora lutea numbers. The fetuses were analyzed...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Diabetes; Rat; Pregnancy; Anomalies; Fatty acid supplementation; Gamaline-V.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000500008