Consulta: creatorFacets:"Shin-ichiro, Kawazu"
Registros recuperados: 2
Data/hora: 03/06/2024 02:42:23

Establishment of an in vitro Transgene Expression System in Epimastigotes of　Trypanosoma congolense
Provedor de dados: Obihiro University of Agriculture and Veterinary Medicine Academic Repository (OAK)
Autores: Sakurai, Tatsuya; Tanaka, Miho; Shin-ichiro, Kawazu; Inoue, Noboru; 井上, 昇.
The epimastigote form (EMF) of Trypanosoma congolense appears in the late tsetse infective stage. Epimastigotes adhere to the tsetse proboscis, proliferate in this region, and differentiate into mammal-infective metacyclic forms (MCFs). This differentiation is called metacyclogenesis and is indispensable for cyclical transmission of the parasite. Although an in vitro culture method reproducing metacyclogenesis was established several decades ago, few genetic tools have been utilized to elucidate the molecular mechanisms underlying T. congolense metacyclogenesis. In this study, we established a transgene expression system in the EMF of T. congolense IL3000; the EMF was successfully cultured and observed to undergo metacyclogenesis in vitro. The newly...
Palavras-chave: Trypanosoma congolense; Epimastigotes; In vitro metacyclogenesis; Transfection; Transgene expression.
Ano: 2009
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2677

自殺原虫による多機能ワクチンの開発研究
Provedor de dados: Obihiro University of Agriculture and Veterinary Medicine Academic Repository (OAK)
Autores: 杉本, 千尋; 河津, 信一郎; 井上, 昇; Chihiro, Sugimoto; Shin-ichiro, Kawazu; Noboru, Inoue.
発行年は推定
Ano: 2007
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3508