Consulta: creatorFacets:"Soares,Killarney Ataide"
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Data/hora: 04/06/2024 17:09:23

Field validation of a Leishmania (Leishmania) mexicana exo-antigens ELISA for diagnosing tegumentary leishmaniasis in regions of Leishmania (Viannia) predominance
Provedor de dados: 55
Autores: Soares,Killarney Ataide; Urdapilleta,Ada Amália Ayala; Santos,Gilcilene Maria dos; Carneiro,Andréa Lisboa; Gomes,Ciro Martins; Roselino,Ana Maria; Sampaio,Raimunda Nonata Ribeiro.
Background: Several tests are performed to obtain better accuracy when diagnosing American tegumentary leishmaniasis (ATL). It is believed that antigens released via secretion, excretion and metabolism are more specific than are antigens released by the lysis of Leishmaniaparasites. Such antigens are known as exo-antigens (exo-Ag) and are formed from products released by cultured parasites in a way that is similar to that in which they cause infections in hosts.Objective: We attempted to validate a Leishmania mexicanaELISA exo-Ag for ATL diagnosis in Midwestern Brazil.Methods: A total of 281 patients were included in the study. We analysed pre-treatment blood from 98 ATL patients; out of those, 85.7% and 14.3% had cutaneous and mucosal forms,...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Diagnostics; Disease control; Infectious disease; Leishmaniasis.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000300302