Consulta: creatorFacets:"Souza,D.O."
Registros recuperados: 3
Data/hora: 09/06/2024 15:49:46

Qualidade seminal e perfil metabólico de caprinos alimentados com semente de linhaça na dieta
Provedor de dados: Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Autores: Souza,R.S.; Barbosa,L.P.; Pinheiro,A.M.; Machado,W.M.; Mendes,C.S.; Araujo,M.L.; Souza,D.O.; Santana,A.L.A.
RESUMO O objetivo da presente pesquisa foi avaliar o efeito da inclusão de semente de linhaça na dieta sobre a qualidade seminal e o perfil metabólico de machos caprinos. Foram utilizados 16 machos da raça Saanen, distribuídos aleatoriamente em quatro grupos, recebendo níveis de inclusão de semente de linhaça (0, 4, 8 e 12%) na dieta, durante um período de 60 dias. As coletas e as avaliações seminais foram realizadas duas vezes por semana. Os animais foram submetidos a coletas quinzenais de sangue, durante todo o período experimental. Os dados foram avaliados por ANOVA e pela análise de regressão a 5% de significância. Houve comportamento cúbico para motilidade espermática progressiva, que apresentou o maior valor (82,30%) com a adição de 9,92% de semente...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Ácido alfalinolênico; Perfil lipídico; Reprodução.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000300899

Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Aschner,M.; Syversen,T.; Souza,D.O.; Rocha,J.B.T.; Farina,M.
This review addresses the mechanisms of methylmercury (MeHg)-induced neurotoxicity, specifically examining the role of oxidative stress in mediating neuronal damage. A number of critical findings point to a central role for astrocytes in mediating MeHg-induced neurotoxicity as evidenced by the following observations: a) MeHg preferentially accumulates in astrocytes; b) MeHg specifically inhibits glutamate uptake in astrocytes; c) neuronal dysfunction is secondary to disturbances in astrocytes. The generation of reactive oxygen species (ROS) by MeHg has been observed in various experimental paradigms. For example, MeHg enhances ROS formation both in vivo (rodent cerebellum) and in vitro (isolated rat brain synaptosomes), as well as in neuronal and mixed...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Methylmercury neurotoxicity; Oxidative stress; Glutamate and selenocompounds; Reactive oxygen species; Astrocytes.
Ano: 2007
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000300001

Effect of inhibitory avoidance training on [3H]-glutamate binding in the hippocampus and parietal cortex of rats
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Schröder,N.; de-Paris,F.; Roesler,R.; Medina,J.H.; Souza,D.O.; Izquierdo,I.
Glutamate receptors have been implicated in memory formation. The aim of the present study was to determine the effect of inhibitory avoidance training on specific [3H]-glutamate binding to membranes obtained from the hippocampus or parietal cortex of rats. Adult male Wistar rats were trained (0.5-mA footshock) in a step-down inhibitory avoidance task and were sacrificed 0, 5, 15 or 60 min after training. Hippocampus and parietal cortex were dissected and membranes were prepared and incubated with 350 nM [3H]-glutamate (N = 4-6 per group). Inhibitory avoidance training induced a 29% increase in glutamate binding in hippocampal membranes obtained from rats sacrificed at 5 min (P&amp;lt;0.01), but not at 0, 15, or 60 min after training, and did not affect...
Tipo: Info:eu-repo/semantics/other
Palavras-chave: Glutamate receptor hippocampus parietal cortex long-term potentiation emotional learning; Memory.
Ano: 2000
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000200011