Consulta: creatorFacets:"Stumpf,W.E."
Registros recuperados: 2
Data/hora: 10/06/2024 18:04:33

Receptor localization of steroid hormones and drugs: discoveries through the use of thaw-mount and dry-mount autoradiography
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Stumpf,W.E.
The history of receptor autoradiography, its development and applications, testify to the utility of this histochemical technique for localizing radiolabeled hormones and drugs at cellular and subcellular sites of action in intact tissues. Localization of diffusible compounds has been a challenge that was met through the introduction of the "thaw-mount" and "dry-mount" autoradiographic techniques thirty years ago. With this cellular receptor autoradiography, used alone or combined with other histochemical techniques, sites of specific binding and deposition in vivo and in vitro have been characterized. Numerous discoveries, some reviewed in this article, provided information that led to new concepts and opened new areas of research. As an example, in...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Vitamin D; Steroid hormones; Receptors; Autoradiography; Drug distribution; Localization.
Ano: 1998
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000200003

Considerations about the present and future use of autoradiography
Provedor de dados: Brazilian Journal of Medical and Biological Research
Autores: Stumpf,W.E.
Tipo: Info:eu-repo/semantics/other
Ano: 1998
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000200001