Consulta: creatorFacets:"Tetreau, Guillaume"
Registros recuperados: 10
Data/hora: 01/06/2024 18:30:50

Deciphering the molecular mechanisms of mother-to-egg immune protection in the mealworm beetle Tenebrio molitor
Provedor de dados: Institutional Archive of Ifreme (ArchiMer)
Autores: Tetreau, Guillaume; Dhinaut, Julien; Galinier, Richard; Audant-lacour, Pascaline; Voisin, Sébastien N; Arafah, Karim; Chogne, Manon; Hilliou, Frédérique; Bordes, Anaïs; Sabarly, Camille; Chan, Philippe; Walet-balieu, Marie-laure; Vaudry, David; Duval, David; Bulet, Philippe; Coustau, Christine; Moret, Yannick; Gourbal, Benjamin.
In a number of species, individuals exposed to pathogens can mount an immune response and transmit this immunological experience to their offspring, thereby protecting them against persistent threats. Such vertical transfer of immunity, named trans-generational immune priming (TGIP), has been described in both vertebrates and invertebrates. Although increasingly studied during the last decade, the mechanisms underlying TGIP in invertebrates are still elusive, especially those protecting the earliest offspring life stage, i.e. the embryo developing in the egg. In the present study, we combined different proteomic and transcriptomic approaches to determine whether mothers transfer a “signal” (such as fragments of infecting bacteria), mRNA and/or...
Tipo: Text
Ano: 2020
URL: https://archimer.ifremer.fr/doc/00655/76684/77815.pdf

Identification and expression profile analysis of odorant binding protein and chemosensory protein genes in Bemisia tabaci MED by head transcriptome
Provedor de dados: Institutional Archive of Ifreme (ArchiMer)
Autores: Wang, Ran; Li, Fengqi; Zhang, Wei; Zhang, Xiaoman; Qu, Cheng; Tetreau, Guillaume; Sun, Lujuan; Luo, Chen; Zhou, Jingjiang.
Odorant binding proteins (OBPs) and chemosensory proteins (CSPs) of arthropods are thought to be involved in chemical recognition which regulates pivotal behaviors including host choice, copulation and reproduction. In insects, OBPs and CSPs located mainly in the antenna but they have not been systematically characterized yet in Bemisia tabaci which is a cryptic species complex and could damage more than 600 plant species. In this study, among the 106,893 transcripts in the head assembly, 8 OBPs and 13 CSPs were identified in B. tabaci MED based on head transcriptomes of adults. Phylogenetic analyses were conducted to investigate the relationships of B. tabaci OBPs and CSPs with those from several other important Hemipteran species, and the motif-patterns...
Tipo: Text
Ano: 2017
URL: https://archimer.ifremer.fr/doc/00663/77537/79351.pdf

Natural resistance to Fasciola hepatica (Trematoda) in Pseudosuccinea columella snails: A review from literature and insights from comparative “omic” analyses
Provedor de dados: Institutional Archive of Ifreme (ArchiMer)
Autores: Alba, Annia; Tetreau, Guillaume; Chaparro, Cristian; Sánchez, Jorge; Vázquez, Antonio A.; Gourbal, Benjamin.
The snail Pseudosuccinea columella is one of the main vectors of the medically-important trematode Fasciola hepatica. In Cuba, the existence of natural P. columella populations that are either susceptible or resistant to F. hepatica infection offers a unique snail-parasite for study of parasite-host compatibility and immune function in gastropods. Here, we review all previous literature on this system and present new “omic” data that provide a molecular baseline of both P. columella phenotypes from naïve snails. Comparison of whole snail transcriptomes (RNAseq) and the proteomes of the albumen gland (2D-electrophoresis, MS) revealed that resistant and susceptible strains differed mainly in an enrichment of particular biological processes/functions and a...
Tipo: Text
Palavras-chave: Transcriptome; Albumen gland; Allocation of resources; Response to stress; Immune defense; Cost of resistance.
Ano: 2019
URL: https://archimer.ifremer.fr/doc/00509/62039/66180.pdf

Effect of crop plants on fitness costs associated with resistance to Bacillus thuringiensis toxins Cry1Ac and Cry2Ab in cabbage loopers
Provedor de dados: Institutional Archive of Ifreme (ArchiMer)
Autores: Wang, Ran; Tetreau, Guillaume; Wang, Ping.
Fitness costs associated with resistance to Bacillus thuringiensis (Bt) toxins critically impact the development of resistance in insect populations. In this study, the fitness costs in Trichoplusia ni strains associated with two genetically independent resistance mechanisms to Bt toxins Cry1Ac and Cry2Ab, individually and in combination, on four crop plants (cabbage, cotton, tobacco and tomato) were analyzed, in comparison with their near-isogenic susceptible strain. The net reproductive rate (R-0) and intrinsic rate of increase (r) of the T. ni strains, regardless of their resistance traits, were strongly affected by the host plants. The ABCC2 gene-linked mechanism of Cry1Ac resistance was associated with relatively low fitness costs, while the Cry2Ab...
Tipo: Text
Ano: 2016
URL: https://archimer.ifremer.fr/doc/00317/42841/79517.pdf

Specific Pathogen Recognition by Multiple Innate Immune Sensors in an Invertebrate
Provedor de dados: Institutional Archive of Ifreme (ArchiMer)
Autores: Tetreau, Guillaume; Pinaud, Silvain; Portet, Anais; Galinier, Richard; Gourbal, Benjamin; Duval, David.
Detection of pathogens by all living organisms is the primary step needed to implement a coherent and efficient immune response. This implies a mediation by different soluble and/or membrane-anchored proteins related to innate immune receptors called PRRs (pattern-recognition receptors) to trigger immune signaling pathways. In most invertebrates, their roles have been inferred by analogy to those already characterized in vertebrate homologs. Despite the induction of their gene expression upon challenge and the presence of structural domains associated with the detection of pathogen-associated molecular patterns in their sequence, their exact role in the induction of immune response and their binding capacity still remain to be demonstrated. To this...
Tipo: Text
Palavras-chave: Invertebrate innate immunity; Interactome; Pathogen sensing; Biomphalaria glabrata; Pattern-recognition receptor; Proteomic profiling; Immune specificity; Hemocyte-free hemolymph.
Ano: 2017
URL: https://archimer.ifremer.fr/doc/00405/51633/71796.pdf

Glabralysins, Potential New β-Pore-Forming Toxin Family Members from the Schistosomiasis Vector Snail Biomphalaria glabrata
Provedor de dados: Institutional Archive of Ifreme (ArchiMer)
Autores: Lassalle, Damien; Tetreau, Guillaume; Pinaud, Silvain; Galinier, Richard; Crickmore, Neil; Gourbal, Benjamain; Duval, David.
Biomphalaria glabrata is a freshwater Planorbidae snail. In its environment, this mollusk faces numerous microorganisms or pathogens, and has developed sophisticated innate immune mechanisms to survive. The mechanisms of recognition are quite well understood in Biomphalaria glabrata, but immune effectors have been seldom described. In this study, we analyzed a new family of potential immune effectors and characterized five new genes that were named Glabralysins. The five Glabralysin genes showed different genomic structures and the high degree of amino acid identity between the Glabralysins, and the presence of the conserved ETX/MTX2 domain, support the hypothesis that they are pore-forming toxins. In addition, tertiary structure prediction confirms that...
Tipo: Text
Palavras-chave: Pore-forming toxin; Cry toxin; Invertebrate; Biomphalaria glabrata; Host; Pathogen; Vector snail; Innate immunity.
Ano: 2020
URL: https://archimer.ifremer.fr/doc/00601/71267/69655.pdf

Interaction between Insects, Toxins, and Bacteria: Have We Been Wrong So Far?
Provedor de dados: Institutional Archive of Ifreme (ArchiMer)
Autores: Tetreau, Guillaume.
Toxins are a major virulence factor produced by many pathogenic bacteria. In vertebrates, the response of hosts to the bacteria is inseparable from the response to the toxins, allowing a comprehensive understanding of this tripartite host-pathogen-toxin interaction. However, in invertebrates, this interaction has been investigated by two complementary but historically distinct fields of research: toxinology and immunology. In this article, I highlight how such dichotomy between these two fields led to a biased, or even erroneous view of the ecology and evolution of the interaction between insects, toxins, and bacteria. I focus on the reason behind such a dichotomy, on how to bridge the fields together, and on confounding effects that could bias the outcome...
Tipo: Text
Palavras-chave: Invertebrate immunity; Host-pathogens interaction; Toxins; Bacillus thuringiensis; Resistance.
Ano: 2018
URL: https://archimer.ifremer.fr/doc/00457/56834/78950.pdf

New Insights Into Biomphalysin Gene Family Diversification in the Vector Snail Biomphalaria glabrata
Provedor de dados: Institutional Archive of Ifreme (ArchiMer)
Autores: Pinaud, Silvain; Tetreau, Guillaume; Poteaux, Pierre; Galinier, Richard; Chaparro, Cristian; Lassalle, Damien; Portet, Anaïs; Simphor, Elodie; Gourbal, Benjamin; Duval, David.
Aerolysins initially characterized as virulence factors in bacteria are increasingly found in massive genome and transcriptome sequencing data from metazoans. Horizontal gene transfer has been demonstrated as the main way of aerolysin-related toxins acquisition in metazoans. However, only few studies have focused on their potential biological functions in such organisms. Herein, we present an extensive characterization of a multigene family encoding aerolysins - named biomphalysin - in Biomphalaria glabrata snail, the intermediate host of the trematode Schistosoma mansoni. Our results highlight that duplication and domestication of an acquired bacterial toxin gene in the snail genome result in the acquisition of a novel and diversified toxin family....
Tipo: Text
Palavras-chave: Biomphalaria; Biomphalysin; Aerolysin; Invertebrate immunity; Pore-forming toxin (PFT); Structure.
Ano: 2021
URL: https://archimer.ifremer.fr/doc/00687/79909/82814.pdf

Double impact: natural molluscicide for schistosomiasis vector control also impedes development of Schistosoma mansoni cercariae into adult parasites
Provedor de dados: Institutional Archive of Ifreme (ArchiMer)
Autores: Augusto, Ronaldo De Carvalho; Tetreau, Guillaume; Chan, Philippe; Walet-balieu, Marie-laure; Mello-silva, Clelia Christina; Santos, Claudia Portes; Grunau, Christoph.
Background Schistosomiasis has been reported in 78 endemic countries and affects 240 million people worldwide. The digenetic parasite Schistosoma mansoni needs fresh water to compete its life cycle. There, it is susceptible to soluble compounds that can affect directly and/or indirectly the parasite's biology. The cercariae stage is one of the key points in which the parasite is vulnerable to different soluble compounds that can significantly alter the parasite's life cycle. Molluscicides are recommended by the World Health Organization for the control of schistosomiasis transmission and Euphorbia milii latex is effective against snails intermediate hosts. Methodology/Principal findings We used parasitological tools and electron microscopy to verify the...
Tipo: Text
Ano: 2017
URL: https://archimer.ifremer.fr/doc/00398/50960/71803.tif

Trans-generational Immune Priming in Invertebrates: Current Knowledge and Future Prospects
Provedor de dados: Institutional Archive of Ifreme (ArchiMer)
Autores: Tetreau, Guillaume; Dhinaut, Julien; Gourbal, Benjamin; Moret, Yannick.
Trans-generational immune priming (TGIP) refers to the transfer of the parental immunological experience to its progeny. This may result in offspring protection from repeated encounters with pathogens that persist across generations. Although extensively studied in vertebrates for over a century, this phenomenon has only been identified 20 years ago in invertebrates. Since then, invertebrate TGIP has been the focus of an increasing interest, with half of studies published during the last few years. TGIP has now been tested in several invertebrate systems using various experimental approaches and measures to study it at both functional and evolutionary levels. However, drawing an overall picture of TGIP from available studies still appears to be a difficult...
Tipo: Text
Palavras-chave: Trans-generational immune priming; Invertebrate immunity; Host-pathogens interaction; Ecology and evolution; Molecular mechanisms; Scenarios.
Ano: 2019
URL: https://archimer.ifremer.fr/doc/00512/62369/66642.pdf