Consulta: creatorFacets:"Torres-Rasgado,Enrique"
Registros recuperados: 1
Data/hora: 10/06/2024 09:03:44

Differential effects of the methylenetetrahydrofolate reductase polymorphisms (C677T and A1298C) on hematological malignancies among Latinos: a meta-analysis
Provedor de dados: 74
Autores: Garcia-Hernandez,Samanta Celeste; Meneses-Sanchez,Perla; Porchia,Leonardo Martin; Torres-Rasgado,Enrique; Pérez-Fuentes,Ricardo; Gonzalez-Mejia,Martha Elba.
Abstract Our objective was to determine the association between the methylenetetrahydrofolate reductase polymorphisms (C677T and A1298C) and the risk of developing acute lymphoblastic leukemia (ALL), chronic myeloid leukemia (CML), acute myeloid leukemia (AML), and multiple myelomas (MM) in Latinos. PubMed, SCOPUS, EBSCO, LILACS, and other Latin-specific databases were searched for case-control studies that investigated the association between these polymorphisms and hematologic malignancies until November 2017. Genotype distributions were extracted and either fixed-effects or random-effects models were used to calculate the pooled crude odds ratios (ORs) for the heterozygous, homozygous, dominant, recessive, and allelic genetic models. No publication bias...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: MTHFR; Protective factor; Latin America; Leukemia.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572019000400549